Date published: 2025-11-21

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4-Oxoheptanedioic acid (CAS 502-50-1)

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Alternate Names:
4-Ketopimelic acid, 4-Oxopimelic acid
CAS Number:
502-50-1
Molecular Weight:
174.15
Molecular Formula:
C7H10O5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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4-Oxoheptanedioic acid is an important intermediary within the citric acid cycle, produced by the condensation of pyruvate and coenzyme A. It is also a key component of multiple metabolic pathways, such as glycolysis and the pentose phosphate pathway. 4-Oxoheptanedioic acid is used in scientific research applications such as the study of enzyme kinetics. Its has modulatory effects on enzyme activity involved in metabolic pathways. It can act as both substrate and inhibitor of enzymes.


4-Oxoheptanedioic acid (CAS 502-50-1) References

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  2. Haloacetic acid and trihalomethane formation from the chlorination and bromination of aliphatic beta-dicarbonyl acid model compounds.  |  Dickenson, ER., et al. 2008. Environ Sci Technol. 42: 3226-33. PMID: 18522098
  3. Quantitative structure-property relationship for predicting chlorine demand by organic molecules.  |  Luilo, GB. and Cabaniss, SE. 2010. Environ Sci Technol. 44: 2503-8. PMID: 20230049
  4. QSPR for predicting chloroform formation in drinking water disinfection.  |  Luilo, GB. and Cabaniss, SE. 2011. SAR QSAR Environ Res. 22: 489-504. PMID: 21714732
  5. Is there no end to the total syntheses of strychnine? Lessons learned in strategy and tactics in total synthesis.  |  Cannon, JS. and Overman, LE. 2012. Angew Chem Int Ed Engl. 51: 4288-311. PMID: 22431197
  6. Relationship between oxidation level and optical properties of secondary organic aerosol.  |  Lambe, AT., et al. 2013. Environ Sci Technol. 47: 6349-57. PMID: 23701291
  7. Catabolism of (2E)-4-hydroxy-2-nonenal via ω- and ω-1-oxidation stimulated by ketogenic diet.  |  Jin, Z., et al. 2014. J Biol Chem. 289: 32327-32338. PMID: 25274632
  8. Bioactive 4-Oxoheptanedioic Monoamide Derivatives of Proteins and Ethanolaminephospholipids: Products of Docosahexaenoate Oxidation.  |  Guo, J., et al. 2016. Chem Res Toxicol. 29: 1706-1719. PMID: 27618287
  9. Anchimeric-Assisted Spontaneous Hydrolysis of Cyanohydrins Under Ambient Conditions: Implications for Cyanide-Initiated Selective Transformations.  |  Yerabolu, JR., et al. 2017. Chemistry. 23: 8756-8765. PMID: 28474360
  10. Cytotoxic, antimicrobial and antiviral secondary metabolites produced by the plant pathogenic fungus Cytospora sp. CCTU A309.  |  Narmani, A., et al. 2019. Fitoterapia. 134: 314-322. PMID: 30807789
  11. Carbohydrate-Based Micro/Nanocapsules With Controlled External Surface for Medical Applications.  |  Bielski, R., et al. 2020. Front Chem. 8: 545. PMID: 32676496
  12. Manipulating crystallization dynamics through chelating molecules for bright perovskite emitters.  |  Zou, Y., et al. 2021. Nat Commun. 12: 4831. PMID: 34376647
  13. Organic compounds in urban aerosols from Gent, Belgium: Characterization, sources, and seasonal differences  |   and Alena Kubátová, Reinhilde Vermeylen, Magda Claeys, Jan Cafmeyer, Willy Maenhaut. 2002. Journal of Geophysical Research: Atmospheres. 107: ICC 5-1-ICC 5-12.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

4-Oxoheptanedioic acid, 5 g

sc-232939
5 g
$71.00