Date published: 2025-9-18

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4-O-(α-D-Galactopyranosyl)-D-galactose (CAS 80446-85-1)

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Alternate Names:
(2R,3R,4S,5R,6R)-2-(hydroxymethyl)-6-[(2R,3R,4R,5R)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxyoxane-3,4,5-triol
Application:
4-O-(α-D-Galactopyranosyl)-D-galactose is a specific ligand that binds to receptors of uropathogenic E. coli
CAS Number:
80446-85-1
Molecular Weight:
342.34
Molecular Formula:
C12H22O11
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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4-O-(α-D-Galactopyranosyl)-D-galactose is a critical compound in glycobiology research, playing a pivotal role in elucidating carbohydrate recognition and cell-cell interactions. This chemical serves as a model substrate for studying galactosyltransferase enzymes and their specificity towards acceptor molecules. Researchers utilize it to investigate the precise mechanisms underlying glycosylation processes, including enzymatic transfer of galactose residues onto glycoproteins and glycolipids. Additionally, 4-O-(α-D-Galactopyranosyl)-D-galactose serves as a valuable tool in glycobiology assays, such as lectin binding studies and carbohydrate microarray analyses, facilitating the characterization of carbohydrate-binding proteins and their ligands. Moreover, this compound finds application in the synthesis of complex carbohydrates and glycoconjugates for various research purposes, including structural studies, molecular recognition studies, and drug delivery systems. Its versatility and importance in deciphering carbohydrate-mediated biological processes make it an indispensable component in glycobiology research, contributing to advancements in understanding cell signaling, immune response modulation, and disease mechanisms associated with aberrant glycosylation patterns.


4-O-(α-D-Galactopyranosyl)-D-galactose (CAS 80446-85-1) References

  1. Discovery of potent inhibitors of PapG adhesins from uropathogenic Escherichia coli through synthesis and evaluation of galabiose derivatives.  |  Ohlsson, J., et al. 2002. Chembiochem. 3: 772-9. PMID: 12203976
  2. GC Behavior of disaccharide trimethylsilyl oximes.  |  Sanz, ML., et al. 2003. J Chromatogr Sci. 41: 205-8. PMID: 12803809
  3. Structural aspects of binding of α-linked digalactosides to human galectin-1.  |  Miller, MC., et al. 2011. Glycobiology. 21: 1627-41. PMID: 21712397
  4. Abelmoschus eculentus Seed Extract Exhibits In Vitro and In Vivo Anti-Alzheimer's Potential Supported by Metabolomic and Computational Investigation.  |  Bakhsh, HT., et al. 2023. Plants (Basel). 12: PMID: 37376007
  5. Alpha-galactosidase from Mortierella vinacea. Crystallization and properties.  |  Suzuki, H., et al. 1970. J Biol Chem. 245: 781-6. PMID: 5418105
  6. Chemical Syntheses of 4-O-α and-β-D-galactopyranosyl-D-galactose and 3-O-α-and-β-D-galactopyranosyl-D-galactose  |  Chacón-Fuertes, M. Encarnación, and Manuel Martín-Lomas. 1975. Carbohydrate Research. 43: 51-56.
  7. 4-O-α-d-galactopyranosyl-d-galactose: Efficient synthetic routes from "polygalacturonic acid".  |  Dahmén, Jan, et al. 1983. Carbohydrate Research. 113: 219-224.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

4-O-(α-D-Galactopyranosyl)-D-galactose, 5 mg

sc-220988
5 mg
$330.00