4-O-(2,3,4,6-Tetra-O-acetyl-α-D-mannopyranosyl)-D-mannopyranose Tetraacetate (CAS 123809-59-6)

4-O-(2,3,4,6-Tetra-O-acetyl-α-D-mannopyranosyl)-D-mannopyranose Tetraacetate is a crucial compound in carbohydrate chemistry research, particularly in the synthesis of complex oligosaccharides and glycoconjugates. Its mechanism of action revolves around its role as a protecting group, shielding specific hydroxyl groups on the mannopyranose moiety. This protection allows for selective functionalization of other hydroxyl groups on the sugar molecule, facilitating the controlled construction of elaborate carbohydrate structures. Researchers have utilized this compound extensively in the synthesis of oligosaccharide fragments for studying glycan recognition by lectins, enzymes, and antibodies. By strategically deprotecting the acetyl groups, chemists can generate diverse oligosaccharide analogs mimicking natural glycans found on cell surfaces and glycoproteins. Furthermore, 4-O-(2,3,4,6-Tetra-O-acetyl-α-D-mannopyranosyl)-D-mannopyranose Tetraacetate has been instrumental in the preparation of glycoconjugates for vaccine development and immunoassays. Conjugation of these synthetic oligosaccharides to carrier proteins enables the generation of glycoconjugate vaccines against pathogenic bacteria and viruses, exploiting the immunogenicity of carbohydrate epitopes. Additionally, researchers utilize this compound in glycan microarray technology to probe glycan-protein interactions on a high-throughput scale, unraveling the specificities of glycan-binding proteins and deciphering the roles of glycans in cellular recognition processes. Overall, 4-O-(2,3,4,6-Tetra-O-acetyl-α-D-mannopyranosyl)-D-mannopyranose Tetraacetate serves as a valuable tool for the synthesis of structurally diverse oligosaccharides and glycoconjugates, enabling investigations into glycan-mediated biological phenomena and the development of carbohydrate-based research tools.