Date published: 2025-12-3

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4-Nonyl Phenol Diethoxylate (CAS 20427-84-3)

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Alternate Names:
2-[2-(4-nonylphenoxy)ethoxy]ethanol
CAS Number:
20427-84-3
Molecular Weight:
308.46
Molecular Formula:
C19H32O3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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4-Nonyl Phenol Diethoxylate (NPE) is a widely used non-ionic surfactant in various industrial and commercial applications. Derived from ethoxylated nonylphenol, an organic compound derived from phenols, 4-Nonyl Phenol Diethoxylate finds its application in a range of products, including detergents, cleaners, and cosmetics. Furthermore, 4-Nonyl Phenol Diethoxylate plays a significant role in laboratory experiments by modifying the properties of diverse substances. In scientific research, 4-Nonyl Phenol Diethoxylate finds utility in studying protein-lipid interactions and protein analysis. Additionally, it is employed to investigate the impact of surfactants on protein stability and properties, as well as the solubility of proteins. Depending on the specific application, 4-Nonyl Phenol Diethoxylate exhibits diverse mechanisms of action. In the study of protein-lipid interactions, 4-Nonyl Phenol Diethoxylate serves to modify the properties of lipids, enhancing their effective interaction with proteins. When examining proteins, this compound alters their properties, enabling more effective interactions with other molecules. Moreover, in investigations focusing on the solubility of proteins and the influence of surfactants, 4-Nonyl Phenol Diethoxylate aids in modifying protein solubility, facilitating their dissolution in aqueous solutions.


4-Nonyl Phenol Diethoxylate (CAS 20427-84-3) References

  1. Substances with estrogenic activity in effluents of sewage treatment plants in southwestern Germany. 1. Chemical analysis.  |  Spengler, P., et al. 2001. Environ Toxicol Chem. 20: 2133-41. PMID: 11596741
  2. A national-scale assessment of micro-organic contaminants in groundwater of England and Wales.  |  Manamsa, K., et al. 2016. Sci Total Environ. 568: 712-726. PMID: 27073165
  3. Synthesis, Compound, Emulsification, and Antibacterial Activity of Modified 1,2,4-Trizaole Derivatives.  |  Guo, H., et al. 2019. ACS Omega. 4: 9680-9685. PMID: 31460058

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

4-Nonyl Phenol Diethoxylate, 10 mg

sc-477411
10 mg
$300.00