Date published: 2026-4-14

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4-Nitrotoluene (CAS 99-99-0)

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Alternate Names:
1-Methyl-4-nitrobenzene
Application:
4-Nitrotoluene is a para-substituted toluene for proteomics research
CAS Number:
99-99-0
Molecular Weight:
137.14
Molecular Formula:
C7H7NO2
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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4-Nitrotoluene is a para-substituted toluene for proteomics research 4-Nitrotoluene stands as an aromatic compound with extensive utility in crafting a diverse range of organic substances. This colorless solid emits a potent, piquant scent and exhibits high flammability. The production of 4-Nitrotoluene involves the nitration of toluene using nitric acid. This compound assumes a pivotal role as an intermediary in the creation of dyes and explosives, while also finding application in the fabrication of polyurethanes, polyesters, and polyamides. Beyond its industrial applications, 4-Nitrotoluene has found its way into various scientific research undertakings. Its involvement in dye synthesis, as well as its contribution to explosive creation, showcases its multifaceted potential. Notably, the compound plays a part in generating polyurethanes, polyesters, and polyamides. Moreover, it plays a role in the synthesis of nitroaromatics, components in the construction of explosives, propellants, and munitions. The precise mechanism by which 4-Nitrotoluene operates remains somewhat enigmatic. However, prevailing theories attribute its reactivity to the nitro group within the molecule. Functioning as a potent electron-withdrawing entity, this nitro group engages in reactions with other molecules, heightening their reactivity. This inherent reactivity positions 4-Nitrotoluene as useful for synthesizing an array of organic compounds.


4-Nitrotoluene (CAS 99-99-0) References

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  3. Isolation and characterization of a 4-nitrotoluene-oxidizing enzyme from activated sludge by a metagenomic approach.  |  Kimura, N., et al. 2010. Microbes Environ. 25: 133-9. PMID: 21576864
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  7. Dissociation dynamics of 3- and 4-nitrotoluene radical cations: Coherently driven C-NO2 bond homolysis.  |  Ampadu Boateng, D., et al. 2018. J Chem Phys. 148: 134305. PMID: 29626885
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  12. Biodegradation of 4-nitrotoluene by Pseudomonas sp. strain 4NT.  |  Haigler, BE. and Spain, JC. 1993. Appl Environ Microbiol. 59: 2239-43. PMID: 8357257
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Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

4-Nitrotoluene, 100 g

sc-238935
100 g
$15.00