Date published: 2026-2-19

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4-Nitrophthalic Anhydride (CAS 641-70-3)

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Application:
4-Nitrophthalic Anhydride is an intermediate for the synthesis of ABT-472
CAS Number:
641-70-3
Purity:
≥95%
Molecular Weight:
193.11
Molecular Formula:
C8H3NO5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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4-Nitrophthalic Anhydride is an intermediate for the synthesis of a benzimidazole PARP inhibitor I (succinate salt) (ABT-472).


4-Nitrophthalic Anhydride (CAS 641-70-3) References

  1. Potential antitumor agents. 59. Structure-activity relationships for 2-phenylbenzimidazole-4-carboxamides, a new class of 'minimal' DNA-intercalating agents which may not act via topoisomerase II.  |  Denny, WA., et al. 1990. J Med Chem. 33: 814-9. PMID: 2153829
  2. Synthesis and pharmacological evaluation of novel phenyl sulfonamide derivatives designed as modulators of pulmonary inflammatory response.  |  Barbosa, ML., et al. 2012. Molecules. 17: 14651-72. PMID: 23222927
  3. Synthesis and biological characterisation of 18F-SIG343 and 18F-SIG353, novel and high selectivity σ2 radiotracers, for tumour imaging properties.  |  Nguyen, VH., et al. 2013. EJNMMI Res. 3: 80. PMID: 24330526
  4. Experimental and Computational Thermochemistry of 3- and 4-Nitrophthalic Anhydride.  |  García-Castro, MA., et al. 2014. J Phys Chem A. 118: 3820-3826. PMID: 24809659
  5. Experimental and Theoretical Thermochemistry of the Isomers 3- and 4-Nitrophthalimide.  |  Salas-López, K., et al. 2017. J Phys Chem A. 121: 5509-5519. PMID: 28671828
  6. De-Novo Design of Cereblon (CRBN) Effectors Guided by Natural Hydrolysis Products of Thalidomide Derivatives.  |  Heim, C., et al. 2019. J Med Chem. 62: 6615-6629. PMID: 31251063
  7. Selection of Peptides that Associate with Dye-Conjugated Solid Surfaces in a pH-Dependent Manner Using cDNA Display.  |  Terai, T., et al. 2019. ACS Omega. 4: 7378-7384. PMID: 31459836
  8. Synthesis and Chemiluminescent Properties of Amino-Acylated luminol Derivatives Bearing Phosphonium Cations.  |  Pantelia, A., et al. 2019. Molecules. 24: PMID: 31683732
  9. E3 Ligase Ligands in Successful PROTACs: An Overview of Syntheses and Linker Attachment Points.  |  Bricelj, A., et al. 2021. Front Chem. 9: 707317. PMID: 34291038
  10. Synthesis and Human Carbonic Anhydrase I, II, IX, and XII Inhibition Studies of Sulphonamides Incorporating Mono-, Bi- and Tricyclic Imide Moieties.  |  Sethi, KK., et al. 2021. Pharmaceuticals (Basel). 14: PMID: 34358123
  11. Design and synthesis of novel phthalocyanines as potential antioxidant and antitumor agents starting with new synthesized phthalonitrile derivatives.  |  El-Badrawy, AM., et al. 2021. RSC Adv. 11: 34300-34308. PMID: 35497267
  12. 1,4,5,8-Naphthalenetetracarboxylic dianhydride grafted phthalocyanine macromolecules as an anode material for lithium ion batteries.  |  Tao, L., et al. 2021. Nanoscale Adv. 3: 3199-3215. PMID: 36133650
  13. Constructing Highly Li+ Conductive Electrode Electrolyte Interphases for 4.6 V Li||LiCoO2 Batteries via Electrolyte Additive Engineering.  |  Bizuneh, GG., et al. 2023. Small Methods. 7: e2300079. PMID: 37256271

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

4-Nitrophthalic Anhydride, 1 g

sc-206931
1 g
$140.00