Date published: 2026-4-29

1-800-457-3801

SCBT Portrait Logo
Seach Input

4-Nitrocatechol (CAS 3316-09-4)

0.0(0)
Write a reviewAsk a question

Alternate Names:
4-nitrobenzene-1,2-diol; 1,2-Dihydroxy-4-nitrobenzene; 4-Nitropyrocatechol
CAS Number:
3316-09-4
Purity:
97%
Molecular Weight:
155.11
Molecular Formula:
C6H5NO4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

QUICK LINKS

4-Nitrocatechol is a chemical compound that functions as a substrate in various enzymatic assays and biochemical studies. It is known to undergo enzymatic oxidation reactions, particularly with enzymes such as catechol oxidase and tyrosinase. In these reactions, 4-Nitrocatechol serves as a model substrate for studying the catalytic mechanisms and kinetics of these enzymes. Its mechanism of action involves serving as a specific target for enzymatic oxidation, leading to the formation of colored products that can be quantified spectrophotometrically. This allows researchers to investigate the enzymatic activity and inhibition of catechol oxidase and tyrosinase in a controlled experimental setting. 4-Nitrocatechol has been utilized in the development of biosensors and other analytical techniques for detecting and measuring enzymatic activity. Its role in these applications involves providing a reliable and reproducible substrate for studying enzyme kinetics and inhibition, contributing to the advancement of biochemical research.


4-Nitrocatechol (CAS 3316-09-4) References

  1. 4-nitrocatechol as a probe of a Mn(II)-dependent extradiol-cleaving catechol dioxygenase (MndD): comparison with relevant Fe(II) and Mn(II) model complexes.  |  Reynolds, MF., et al. 2003. J Biol Inorg Chem. 8: 263-72. PMID: 12589562
  2. Simultaneous determination of 4-nitroanisole, 4-nitrophenol, and 4-nitrocatechol by phase-sensitive ac polarography.  |  Burgschat, H. and Netter, KJ. 1977. J Pharm Sci. 66: 60-3. PMID: 13196
  3. Soybean lipoxygenase-3 in complex with 4-nitrocatechol.  |  Skrzypczak-Jankun, E., et al. 2004. Acta Crystallogr D Biol Crystallogr. 60: 613-5. PMID: 14993710
  4. Protein engineering of toluene 4-monooxygenase of Pseudomonas mendocina KR1 for synthesizing 4-nitrocatechol from nitrobenzene.  |  Fishman, A., et al. 2004. Biotechnol Bioeng. 87: 779-90. PMID: 15329936
  5. Protein engineering of toluene-o-xylene monooxygenase from Pseudomonas stutzeri OX1 for oxidizing nitrobenzene to 3-nitrocatechol, 4-nitrocatechol, and nitrohydroquinone.  |  Vardar, G., et al. 2005. J Biotechnol. 115: 145-56. PMID: 15607233
  6. 4-Nitrocatechol as a colorimetric probe for non-heme iron dioxygenases.  |  Tyson, CA. 1975. J Biol Chem. 250: 1765-70. PMID: 163257
  7. p-Nitrophenol degradation via 4-nitrocatechol in Burkholderia sp. SJ98 and cloning of some of the lower pathway genes.  |  Chauhan, A., et al. 2010. Environ Sci Technol. 44: 3435-41. PMID: 20359211
  8. para-Nitrophenol 4-monooxygenase and hydroxyquinol 1,2-dioxygenase catalyze sequential transformation of 4-nitrocatechol in Pseudomonas sp. strain WBC-3.  |  Wei, M., et al. 2010. Biodegradation. 21: 915-21. PMID: 20361240
  9. 4-Nitrocatechol production from rho-nitrophenol by rat liver.  |  Chrastil, J. and Wilson, JT. 1975. J Pharmacol Exp Ther. 193: 631-8. PMID: 238027
  10. Photochemical Degradation of 4-Nitrocatechol and 2,4-Dinitrophenol in a Sugar-Glass Secondary Organic Aerosol Surrogate.  |  Dalton, AB. and Nizkorodov, SA. 2021. Environ Sci Technol. 55: 14586-14594. PMID: 34669384
  11. Alterations of host-gut microbiome interactions in multiple sclerosis.  |  Cantoni, C., et al. 2022. EBioMedicine. 76: 103798. PMID: 35094961
  12. Spectrophotometric Determination of Molybdenum(VI) as a Ternary Complex with 4-Nitrocatechol and Benzalkonium Chloride.  |  Divarova, VV., et al. 2022. Molecules. 27: PMID: 35209004
  13. Properties of a complex of Fe(III)-soybean lipoxygenase-1 and 4-nitrocatechol.  |  Spaapen, LJ., et al. 1980. Biochim Biophys Acta. 617: 132-40. PMID: 6766321

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

4-Nitrocatechol, 1 g

sc-238926
1 g
$26.00