Date published: 2025-12-18

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4-Nitrobenzoic acid (CAS 62-23-7)

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CAS Number:
62-23-7
Molecular Weight:
167.12
Molecular Formula:
C7H5NO4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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4-Nitrobenzoic acid (4-NBA) is an organic compound. This white crystalline solid exhibits solubility in organic solvents and slight solubility in water. It holds significance as an intermediate in the synthesis of various organic compounds and finds wide-ranging applications in analytical and biochemical fields. The precise mechanism of action of 4-Nitrobenzoic acid is not entirely elucidated. However, it is postulated to engage in interactions with specific enzymes and proteins, inducing changes in their activity levels. Furthermore, it is believed to interact with particular cell receptors, leading to alterations in their activity. Moreover, it is suggested that 4-Nitrobenzoic acid can inhibit certain enzymes, contributing to modifications in their activity. 4-Nitrobenzoic acid has been observed to impact a diverse range of biochemical and physiological processes. It has demonstrated the ability to inhibit the activity of specific enzymes, consequently affecting their functionality. Moreover, it has been found to interact with certain cell receptors, influencing their activity.


4-Nitrobenzoic acid (CAS 62-23-7) References

  1. HPLC analysis of in vivo metabolites of 4-nitrobenzoic acid [(5-nitro-2-thiopheneyl)methylene]hydrazide in rats.  |  Koçyiğit-Kaymakçioğlu, B., et al. 2007. Eur J Drug Metab Pharmacokinet. 32: 197-203. PMID: 18348468
  2. Seven hexamethylenetetramine (HMTA) complexes with mono- and dicarboxylic acids: analysis of packing modes of HMTA complexes in the literature.  |  Lemmerer, A. 2011. Acta Crystallogr B. 67: 177-92. PMID: 21422616
  3. Breaking the ring through a room temperature catalytic Wittig reaction.  |  O'Brien, CJ., et al. 2013. Chemistry. 19: 5854-8. PMID: 23526683
  4. The (•)OH radical yield in the H2O2 + O3 (peroxone) reaction.  |  Fischbacher, A., et al. 2013. Environ Sci Technol. 47: 9959-64. PMID: 23883394
  5. 4-Nitrobenzoic acid reductase of the nematode Ascaris lumbricoides var suum. Localization of the enzyme and optimum assay conditions.  |  Douch, PG. 1975. Xenobiotica. 5: 293-302. PMID: 239490
  6. Investigation of supramolecular synthons and structural characterisation of aminopyridine-carboxylic acid derivatives.  |  Hemamalini, M., et al. 2014. Chem Cent J. 8: 31. PMID: 24887234
  7. 4-Nitrophenyl- and 4'-nitro-1,1'-biphenyl-4-carboxylates attached to Mo2 quadruple bonds: ground versus excited state M2δ-ligand conjugation.  |  Alberding, BG., et al. 2014. Dalton Trans. 43: 11397-403. PMID: 24930899
  8. The structures of the isomorphous potassium and rubidium salts of 4-nitrobenzoic acid and an overview of the metal complex stereochemistries of the alkali metal salt series with this ligand.  |  Smith, G. 2015. Acta Crystallogr C Struct Chem. 71: 499-505. PMID: 26044333
  9. The first examples of multiply bonded dirhenium(iii,ii) paramagnetic complexes containing nitrobenzoate ligands: spectroscopic, structural, cytotoxicity and computational studies.  |  Mallick, S., et al. 2017. Dalton Trans. 46: 5670-5679. PMID: 28181614
  10. New Biocatalyst Including a 4-Nitrobenzoic Acid Mediator Embedded by the Cross-Linking of Chitosan and Genipin and Its Use in an Energy Device.  |  Hyun, K., et al. 2020. ACS Appl Mater Interfaces. 12: 23635-23643. PMID: 32343553
  11. 2-Chloro-4-nitrobenzoic acid as a coformer with pharmaceutical cocrystals and molecular salts.  |  Lemmerer, A. 2020. Acta Crystallogr C Struct Chem. 76: 746-752. PMID: 32756037
  12. Effects of Silver Carbonate and p-Nitrobenzoic Acid for Accelerating Palladium-Catalyzed Allylic C-H Acyloxylation.  |  Skhiri, A., et al. 2021. Org Lett. 23: 7044-7048. PMID: 34432479
  13. Taurine conjugates as metabolites of arylacetic acids in the ferret.  |  Idle, JR., et al. 1978. Xenobiotica. 8: 253-64. PMID: 347725
  14. Nematicidal activity of furanoeremophilenes against Meloidogyne incognita and Nacobbus aberrans.  |  Velasco-Azorsa, R., et al. 2022. Pest Manag Sci. 78: 2571-2580. PMID: 35338557
  15. Influence of the gut microflora on the metabolism of 4-nitrobenzoic acid in the marmoset.  |  Kuzniar, EJ. and James, SP. 1981. Xenobiotica. 11: 675-83. PMID: 6976659

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

4-Nitrobenzoic acid, 100 g

sc-238920A
100 g
$20.00

4-Nitrobenzoic acid, 250 g

sc-238920
250 g
$41.00

4-Nitrobenzoic acid, 1 kg

sc-238920B
1 kg
$71.00

4-Nitrobenzoic acid, 5 kg

sc-238920C
5 kg
$306.00

4-Nitrobenzoic acid, 10 kg

sc-238920D
10 kg
$551.00