Date published: 2025-12-25

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4-Nitrobenzaldehyde oxime (CAS 1129-37-9)

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Alternate Names:
4-Nitrobenzaldoxime
CAS Number:
1129-37-9
Molecular Weight:
166.13
Molecular Formula:
C7H6N2O3
Supplemental Information:
This is as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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4-Nitrobenzaldehyde oxime, known as 4-NOA, is an oxime compound categorized within the class of aldehydic oximes. It features a nitro group situated at the para position of the benzene ring. 4-Nitrobenzaldehyde oxime serves as a versatile reagent extensively utilized in numerous organic synthesis reactions, making it indispensable in scientific research. In organic synthesis, 4-Nitrobenzaldehyde oxime plays a pivotal role as a catalyst, facilitating the reaction between two molecules to generate a new product. This catalytic function is particularly notable in the "Michael reaction," a fundamental process employed in the synthesis of various organic compounds. Additionally, 4-Nitrobenzaldehyde oxime acts as a proton donor, contributing protons to molecules participating in the reaction. This proton donation enhances the reaction rate and augments the yield of the desired product.


4-Nitrobenzaldehyde oxime (CAS 1129-37-9) References

  1. 3,4-Bis(4-nitro-phen-yl)-1,2,5-oxadiazole 2-oxide.  |  Alhouari, G., et al. 2008. Acta Crystallogr Sect E Struct Rep Online. 64: o511. PMID: 21201530
  2. Crystal structure and hydrogen bonding study of (10E)-2,2-dimethyl-3,4-dihydro-2H-benzo[g]chromene-5,10-dione 10-oxime derived from α-lapachone.  |  da Silva, AR., et al. 2011. Molecules. 16: 1192-200. PMID: 21273950
  3. A study on quantum chemical calculations of 3-, 4-nitrobenzaldehyde oximes.  |  Gökce, H. and Bahçeli, S. 2011. Spectrochim Acta A Mol Biomol Spectrosc. 79: 1783-93. PMID: 21683648
  4. Gallium-containing polymer brush film as efficient supported Lewis acid catalyst in a glass microreactor.  |  Munirathinam, R., et al. 2013. Beilstein J Org Chem. 9: 1698-704. PMID: 24062830
  5. Use of hydroxylamines, hydroxamic acids, oximes and amines as nucleophiles in the Zbiral oxidative deamination of N-acetyl neuraminic acid. Isolation and characterization of novel mono- and disubstitution products.  |  Hawsawi, M., et al. 2020. Carbohydr Res. 490: 107921. PMID: 32171977

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

4-Nitrobenzaldehyde oxime, 5 g

sc-256810
5 g
$228.00