4-n-Octylbenzoylamido-propyl-dimethylammoniosulfobetaine (CAS 216667-49-1)

4-n-Octylbenzoylamido-propyl-dimethylammoniosulfobetaine is a zwitterionic surfactant widely utilized in research for its unique properties and versatile applications. Its mechanism of action stems from its amphiphilic structure, comprising both hydrophobic and hydrophilic moieties. This allows it to form micelles in aqueous solutions, with the hydrophobic tails orienting towards the interior and the hydrophilic headgroups facing outward. In research, this compound has been extensively employed in various biochemical and biophysical studies, particularly in protein solubilization and stabilization. Its ability to form micelles around hydrophobic regions of proteins aids in maintaining their native structure and function in solution, facilitating their characterization through techniques such as nuclear magnetic resonance (NMR) spectroscopy and X-ray crystallography. Additionally, 4-n-Octylbenzoylamido-propyl-dimethylammoniosulfobetaine has found applications in membrane protein research, where it serves as a detergent for membrane solubilization and extraction. Its mild solubilizing properties make it suitable for maintaining the structural integrity of membrane proteins, enabling their functional and structural studies. Moreover, this compound has been utilized in various other research areas, including drug delivery, cell biology, and biotechnology, highlighting its broad utility and significance in scientific investigations.