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4-Methylumbelliferyl palmitate (CAS 17695-48-6)

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Alternate Names:
4-Methylumbelliferyl palmitate is also known as 4-MUP.
Application:
4-Methylumbelliferyl palmitate is a fluorogenic substrate for lysosomal acid lipase in human leukocytes.
CAS Number:
17695-48-6
Purity:
≥97%
Molecular Weight:
414.59
Molecular Formula:
C26H38O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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4-Methylumbelliferyl palmitate is a fluorogenic substrate for lipase in human leukocytes. Lysosomal acid lipase can cleave 4-Methylumbelliferyl palmitate to release a fluorescent moiety. 4-Methylumbelliferyl palmitate may also be cleaved by different acid lipases as well. 4-Methylumbelliferyl palmitate can be used to assess lysosomal acid lipase activity in small scale blood samples.


4-Methylumbelliferyl palmitate (CAS 17695-48-6) References

  1. Effect of dimethylsulfoxide on hydrolysis of lipase.  |  Tsuzuki, W., et al. 2001. Biosci Biotechnol Biochem. 65: 2078-82. PMID: 11676024
  2. Polar organic solvent added to an aqueous solution changes hydrolytic property of lipase.  |  Tsuzuki, W., et al. 2003. Biosci Biotechnol Biochem. 67: 1660-6. PMID: 12951497
  3. A new method for the measurement of lysosomal acid lipase in dried blood spots using the inhibitor Lalistat 2.  |  Hamilton, J., et al. 2012. Clin Chim Acta. 413: 1207-10. PMID: 22483793
  4. Properties of partially purified esterase in human crystalline lens and variation in its enzyme activity during aging and with advance of senile cataract.  |  Kamei, A. 1996. Biol Pharm Bull. 19: 1223-6. PMID: 8889046

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

4-Methylumbelliferyl palmitate, 250 mg

sc-214256
250 mg
$163.00

4-Methylumbelliferyl palmitate, 500 mg

sc-214256B
500 mg
$224.00

4-Methylumbelliferyl palmitate, 1 g

sc-214256A
1 g
$396.00

4-Methylumbelliferyl palmitate, 2 g

sc-214256C
2 g
$546.00

4-Methylumbelliferyl palmitate, 5 g

sc-214256D
5 g
$876.00

When will it be shipped if ordered today?

Asked by: LBJM
Thank you for your question. Please contact our Customer Care Department for current product availability.
Answered by: Technical Support
Date published: 2019-10-07

Hi would this reagent cross react with mouse lipase?

Asked by: agga
Thank you for your question. We have found a reference about this chemical, 4-Methylumbelliferyl palmitate (CAS 17695-48-6), that you might find helpful, PMID: 3940274. It appears this can be used as a substrate for human or mouse.
Answered by: Technical Support
Date published: 2017-02-06
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Rated 5 out of 5 by from GuyGuy, et al. (PubMed ID 25151) used 4-methylumbelliferyl palmitate as a substrate to study the levels of acid esterase in cultured skin fibroblasts and amniotic fluid cells. -SCBT Publication Review
Date published: 2015-05-24
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4-Methylumbelliferyl palmitate is rated 5.0 out of 5 by 1.
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