4-Methylumbelliferyl caprylate (CAS 20671-66-3)
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4-Methylumbelliferyl caprylate (4-MUC) is a fluorogenic substrate for esterase with C8 activity yielding a blue fluorescent solution upon cleavage. It is employed in the identification of Salmonella spp. based on the detection of caprylate esterase. 4-Methylumbelliferyl caprylate has been used in a variety of laboratory experiments, including enzymology, cell biology, and biochemistry. It has been utilized to study the enzymatic activity of lipases, proteases, and other enzymes. It has also been used to monitor the activity of cell signaling pathways, such as the MAPK and JAK-STAT pathways. Additionally, 4-Methylumbelliferyl caprylate is used for the detection of protein-protein interactions and for the analysis of enzyme kinetics.
4-Methylumbelliferyl caprylate (CAS 20671-66-3) References
- A high-throughput screen for endothelial lipase using HDL as substrate. | Keller, PM., et al. 2008. J Biomol Screen. 13: 468-75. PMID: 18566479
- Kinetics of catalyzed hydrolysis of 4-methylumbelliferyl caprylate (MUCAP) salmonella reagent. | Al-Kady, AS., et al. 2011. Spectrochim Acta A Mol Biomol Spectrosc. 79: 1540-5. PMID: 21715222
- Rapid fluorescence method for screening Salmonella spp. from enteric differential agars. | Aguirre, PM., et al. 1990. J Clin Microbiol. 28: 148-9. PMID: 2405010
- A fluorescence-based hydrolytic enzyme activity assay for quantifying toxic effects of Roundup® to Daphnia magna. | Ørsted, M. and Roslev, P. 2015. Environ Toxicol Chem. 34: 1841-50. PMID: 25809520
- Visual detection technique for efficient screening and isolation of Salmonella based on a novel enrichment assay using chromatography membrane. | Tang, F., et al. 2016. Eur J Clin Microbiol Infect Dis. 35: 353-61. PMID: 26796551
- Escherichia coli O157:H7 Strain EDL933 Harbors Multiple Functional Prophage-Associated Genes Necessary for the Utilization of 5-N-Acetyl-9-O-Acetyl Neuraminic Acid as a Growth Substrate. | Saile, N., et al. 2016. Appl Environ Microbiol. 82: 5940-50. PMID: 27474715
- Microfluidic droplet application for bacterial surveillance in fresh-cut produce wash waters. | Harmon, JB., et al. 2020. PLoS One. 15: e0233239. PMID: 32516315
- High-Throughput, Fluorescence-Based Esterase Activity Assay for Assessing Polysorbate Degradation Risk during Biopharmaceutical Development. | Bhargava, AC., et al. 2021. Pharm Res. 38: 397-413. PMID: 33655394
- Identification and Characterization of Polysorbate-Degrading Enzymes in a Monoclonal Antibody Formulation. | Graf, T., et al. 2021. J Pharm Sci. 110: 3558-3567. PMID: 34224732
- The measurement and control of high-risk host cell proteins for polysorbate degradation in biologics formulation. | Li, X., et al. 2022. Antib Ther. 5: 42-54. PMID: 35155990
- Design and Development of Magnetic Iron Core Gold Nanoparticle-Based Fluorescent Multiplex Assay to Detect Salmonella. | Zhao, X., et al. 2022. Nanomaterials (Basel). 12: PMID: 36364693
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
4-Methylumbelliferyl caprylate, 2.5 g | sc-281420 | 2.5 g | $194.00 | |||
4-Methylumbelliferyl caprylate, 5 g | sc-281420A | 5 g | $377.00 |