Molecular structure of 4-Methylumbelliferyl β-D-glucuronide, CAS Number: 6160-80-1
4-Methylumbelliferyl β-D-glucuronide (CAS 6160-80-1)
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Alternate Names:
MUG
Application:
4-Methylumbelliferyl β-D-glucuronide is a useful substrate of beta-glucuronidase
CAS Number:
6160-80-1
Purity:
≥99%
Molecular Weight:
352.29
Molecular Formula:
C16H16O9
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Description
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SDS & Certificate of Analysis
4-Methylumbelliferyl β-D-glucuronide is a fluorescent substrate of beta-glucuronidase. Once cleaved, MUG yields blue fluorescence seen under UV light. It is ideal for working with Escherichia coli and plant molecular studies.
4-Methylumbelliferyl β-D-glucuronide (CAS 6160-80-1) References
- Use of enzymatic methods for rapid enumeration of coliforms in freshwaters. | George, I., et al. 2000. J Appl Microbiol. 88: 404-13. PMID: 10747220
- Regulation of human beta-glucuronidase by A23187 and thapsigargin in the hepatoma cell line HepG2. | Sperker, B., et al. 2001. Mol Pharmacol. 59: 177-82. PMID: 11160851
- Determination of UDP-glucuronosyltransferase UGT1A6 activity in human and rat liver microsomes by HPLC with UV detection. | Hanioka, N., et al. 2001. J Pharm Biomed Anal. 25: 65-75. PMID: 11274859
- Hydrolysis of 4-methylumbelliferyl-beta-D-glucuronide in differing sample fractions of river waters and its implication for the detection of fecal pollution. | Farnleitner, AH., et al. 2002. Water Res. 36: 975-81. PMID: 11848369
- Phenotypic and genetic markers for serotype-specific detection of Shiga toxin-producing Escherichia coli O26 strains from North America. | Murinda, SE., et al. 2004. Foodborne Pathog Dis. 1: 125-35. PMID: 15992272
- Comparative study of commercial 4-methylumbelliferyl-beta-D-glucuronide preparations with the Standard Methods membrane filtration fecal coliform test for the detection of Escherichia coli in water samples. | Clark, DL., et al. 1991. Appl Environ Microbiol. 57: 1528-34. PMID: 1854205
- Elucidation of Septoria tritici x Wheat Interactions Using GUS-Expressing Isolates. | Pnini-Cohen, S., et al. 2000. Phytopathology. 90: 297-304. PMID: 18944623
- A biosensor platform for rapid detection of E. coli in drinking water. | Hesari, N., et al. 2016. Enzyme Microb Technol. 83: 22-8. PMID: 26777247
- Enzyme-Responsive Biopolymeric Nanogel Fibers by Extrusion: Engineering of High-Surface-Area Hydrogels and Application in Bacterial Enzyme Detection. | Das, D., et al. 2021. ACS Appl Mater Interfaces. 13: 12928-12940. PMID: 33709691
- Molecular dissection of genes and promoters involved in glycyrrhizin biosynthesis revealed phytohormone induced modulation in Glycyrrhiza glabra L. | Goyal, P., et al. 2022. Gene. 836: 146682. PMID: 35714794
- Engineered Agrobacterium improves transformation by mitigating plant immunity detection. | Yang, F., et al. 2022. New Phytol.. PMID: 36564969
- An evaluation of the use of 4-methylumbelliferyl-beta-D-glucuronide (MUG) in different solid media for the detection and enumeration of Escherichia coli in foods. | Villari, P., et al. 1997. Lett Appl Microbiol. 24: 286-90. PMID: 9134776
- Sensitive method for the quantification of beta-glucuronidase activity in human urine using capillary electrophoresis with fluorescence detection. | Wu, X., et al. 1998. J Chromatogr B Biomed Sci Appl. 708: 61-6. PMID: 9653947
Substrate of:
β-glucuronidase, and Chromogenic.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
4-Methylumbelliferyl β-D-glucuronide, 2 g | sc-280452 | 2 g | $316.00 | |||
4-Methylumbelliferyl β-D-glucuronide, 20 g | sc-280452A | 20 g | $444.00 | |||
4-Methylumbelliferyl β-D-glucuronide, 50 g | sc-280452B | 50 g | $877.00 |