Molecular structure of 4-Methylumbelliferyl 6-thio-palmitate-β-D-glucopyranoside, CAS Number: 229644-17-1
4-Methylumbelliferyl 6-thio-palmitate-β-D-glucopyranoside (CAS 229644-17-1)
Alternate Names:
4-Methylumbelliferyl 6-thio-palmitate-β-D-glucopyranoside is also known as Mu-6S-Palm-β-Glc.
Application:
4-Methylumbelliferyl 6-thio-palmitate-β-D-glucopyranoside is a fluorogenic substrate used in palmitoyl-protein thioesterase assays
CAS Number:
229644-17-1
Molecular Weight:
592.78
Molecular Formula:
C32H48O8S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
4-Methylumbelliferyl 6-thio-palmitate-β-D-glucopyranoside is a fluorogenic substrate in the assay of Palmitoyl-Protein Thioesterase. 4-Methylumbelliferyl 6-thio-palmitate-β-D-glucopyranoside is used in the diagnosis of infantile neuronal ceroid lipofuscinosis (INCL). It has also been used in cell culture studies to investigate the effects of drugs on cell metabolism, DNA and RNA synthesis, protein synthesis, and enzyme activity.
4-Methylumbelliferyl 6-thio-palmitate-β-D-glucopyranoside (CAS 229644-17-1) References
- A rapid fluorogenic palmitoyl-protein thioesterase assay: pre- and postnatal diagnosis of INCL. | van Diggelen, OP., et al. 1999. Mol Genet Metab. 66: 240-4. PMID: 10191108
- The neuronal ceroid-lipofuscinoses. | Goebel, HH. 1995. J Child Neurol. 10: 424-37. PMID: 8576551
- Lysosomal targeting of palmitoyl-protein thioesterase. | Verkruyse, LA. and Hofmann, SL. 1996. J Biol Chem. 271: 15831-6. PMID: 8663305
- Association of mutations in a lysosomal protein with classical late-infantile neuronal ceroid lipofuscinosis. | Sleat, DE., et al. 1997. Science. 277: 1802-5. PMID: 9295267
- Enzymatic and molecular biological analysis of palmitoyl protein thioesterase deficiency in infantile neuronal ceroid lipofuscinosis. | Cho, S. and Dawson, G. 1998. J Neurochem. 71: 323-9. PMID: 9648881
Substrate of:
Enzyme, and Fluorogenic.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
4-Methylumbelliferyl 6-thio-palmitate-β-D-glucopyranoside, 5 mg | sc-220956 | 5 mg | $399.00 |