4-Methylumbelliferyl 6-Sulfo-2-acetamido-2-deoxy-Beta-D-glucopyranoside Potassium Salt MF: C18H20NO11S•K
MW: 497.51
A fluorogenic substrate of GNS.

4-Methylumbelliferyl 6-Sulfo-2-acetamido-2-deoxy-Beta-D-glucopyranoside Potassium Salt

4-Methylumbelliferyl 6-Sulfo-2-acetamido-2-deoxy-β-D-glucopyranoside Potassium Salt | CAS 210357-37-2 is rated 5.0 out of 5 by 1.
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Alternate Names: MUGS
Purity: 98%
Molecular Weight: 497.51
Molecular Formula: C18H20NO11S•K
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).
Submit a review for this product and receive 15 CruzCredits

4-Methylumbelliferyl 6-Sulfo-2-acetamido-2-deoxy-β-D-glucopyranoside, Potassium Salt is a fluorogenic substrate for GNS (lysosomal N-acetylglucosamine-6-sulphate sulphatase). 4-Methylumbelliferyl 6-Sulfo-2-acetamido-2-deoxy-α-D-glucopyranoside, Potassium Salt is a substrate of HEXA.


References

He, W., et al.: J. inher. Metab. Dis., 16, 935 (1993)

Physical State :
Solid
Solubility :
Soluble in methanol (easily), and water (20 mg/ml).
Storage :
Store at -20° C
Melting Point :
195-197° C
Fluoresence :
λex 360 nm, λem 440 nm
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
71307144
MDL Number :
MFCD00797620
SMILES :
CC1=CC(=O)OC2=C1C=CC(=C2)O[[email protected]@H]3[[email protected]]([[email protected]]([[email protected]]([[email protected]@H](O3)CO[S](=O)(=O)[O-])O)O)NC(=O)C.[K+]

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Certificate of Analysis

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I read articles that this substrate from another company (synonym 4-Methylumbelliferyl-6-sulfo-N-acetyl-β-D-glucosaminide, Potassium Salt) is used for Hexosaminidase A activity.Is your product also suitable for Hexosaminidase A enzyme activity?

Asked by: hande
Thanks for your question. Yes, the sc-223640 is a substrate of HEXA and can be used for Hexosaminidase A activity. Please contact Technical service for further support.
Answered by: SCBT Heidelberg Support
Date published: 2019-01-06
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Rated 5 out of 5 by from Various publications cite the use of 4 Various publications cite the use of 4-Methylumbelliferyl 6-Sulfo-2-acetamido-2-deoxy- -D-glucopyranoside Potassium Salt as a fluorogenic substrate of GNS. -SCBT Publication Review
Date published: 2015-02-25
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