Date published: 2026-4-27

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4-(Methylthio)butylnitrile (CAS 59121-24-3)

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Alternate Names:
4-(Methylthio)butanenitrile; 4-(Methylthio)butyronitrile; 3-Methylthiopropyl Cyanide
Application:
4-(Methylthio)butylnitrile is a compound produced by induced or natural fermentation
CAS Number:
59121-24-3
Molecular Weight:
115.20
Molecular Formula:
C5H9NS
Supplemental Information:
This is as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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4-(Methylthio)butylnitrile is an organic compound containing sulfur. This colorless, highly flammable liquid possesses a potent odor. It plays an indispensable role in the synthesis of a variety of organic compounds, including those used in agrochemicals, dyes, rubber, and plastics production. Beyond these uses, it holds a significant place in scientific research, acting as a reagent in organic synthesis and contributing to the creation of other sulfur-inclusive compounds like thioureas and thioamides. While the full mechanism of action of 4-(Methylthio)butylnitrile remains unclear, it′s believed to be associated with the formation of a thiocarbonate intermediate that is subsequently hydrolyzed to yield the final product. Additionally, its reaction with thionyl chloride or sodium sulfide is thought to produce a thiocyanate intermediate that, after hydrolysis, forms the end product.


4-(Methylthio)butylnitrile (CAS 59121-24-3) References

  1. Verticillium suppression is associated with the glucosinolate composition of Arabidopsis thaliana leaves.  |  Witzel, K., et al. 2013. PLoS One. 8: e71877. PMID: 24039726
  2. Verticillium longisporum infection induces organ-specific glucosinolate degradation in Arabidopsis thaliana.  |  Witzel, K., et al. 2015. Front Plant Sci. 6: 508. PMID: 26217360
  3. Cytotoxic and genotoxic potential of food-borne nitriles in a liver in vitro model.  |  Kupke, F., et al. 2016. Sci Rep. 6: 37631. PMID: 27883018
  4. Comprehensive Volatilome Signature of Various Brassicaceae Species.  |  Lukić, I., et al. 2023. Plants (Basel). 12: PMID: 36616312

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

4-(Methylthio)butylnitrile, 200 mg

sc-209857
200 mg
$360.00