Molecular structure of 4-Methylpyrazole hydrochloride, CAS Number: 56010-88-9
4-Methylpyrazole hydrochloride (CAS 56010-88-9)
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Application:
4-Methylpyrazole hydrochloride is a product for proteomics research
CAS Number:
56010-88-9
Molecular Weight:
118.56
Molecular Formula:
C4H6N2•HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Description
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SDS & Certificate of Analysis
4-Methylpyrazole hydrochloride is an ADH (alcohol dehydrogenase) inhibitor. 4-Methylpyrazole hydrochloride is also an antidote in methanol and ethylene glycol poisoning. It acts as a substrate for various enzymes, which catalyze the reaction of the compound to form other compounds. In addition, 4-Methylpyrazole hydrochloride can act as an inhibitor of enzymes, blocking their action and preventing the formation of other compounds.
4-Methylpyrazole hydrochloride (CAS 56010-88-9) References
- The metabolism of beta-chloroprene: preliminary in-vitro studies using liver microsomes. | Himmelstein, MW., et al. 2001. Chem Biol Interact. 135-136: 267-84. PMID: 11397396
- Characterization of the metabolic interaction between trihalomethanes and chloroacetic acids using rat liver microsomes. | St-Pierre, A., et al. 2005. J Toxicol Environ Health A. 68: 287-98. PMID: 15799452
- Aldehydes release zinc from proteins. A pathway from oxidative stress/lipid peroxidation to cellular functions of zinc. | Hao, Q. and Maret, W. 2006. FEBS J. 273: 4300-10. PMID: 16930132
- Oral fomepizole administration to treat ethylene glycol and methanol poisonings: advantages and limitations. | Mégarbane, B., et al. 2008. Clin Toxicol (Phila). 46: 1097; author reply 1097-8. PMID: 18763149
- Ethanol augments RANTES/CCL5 expression in rat liver sinusoidal endothelial cells and human endothelial cells via activation of NF-kappa B, HIF-1 alpha, and AP-1. | Yeligar, SM., et al. 2009. J Immunol. 183: 5964-76. PMID: 19828633
- In vitro studies on the oxidative metabolism of 20(s)-ginsenoside Rh2 in human, monkey, dog, rat, and mouse liver microsomes, and human liver s9. | Li, L., et al. 2012. Drug Metab Dispos. 40: 2041-53. PMID: 22829543
- High-throughput screening for growth inhibitors using a yeast model of familial paraganglioma. | Bancos, I., et al. 2013. PLoS One. 8: e56827. PMID: 23451094
- Differential metabolism of 4-hydroxynonenal in liver, lung and brain of mice and rats. | Zheng, R., et al. 2014. Toxicol Appl Pharmacol. 279: 43-52. PMID: 24832492
- Alcohol Dehydrogenases and Acetaldehyde Dehydrogenases are Beneficial for Decidual Stromal Cells to Resist the Damage from Alcohol. | Li, ZL., et al. 2017. Alcohol Alcohol. 52: 180-189. PMID: 28182209
- Ethanol-triggered Lipophagy Requires SQSTM1 in AML12 Hepatic Cells. | Wang, L., et al. 2017. Sci Rep. 7: 12307. PMID: 28951592
- Cytochrome P450 enzymes contribute to the metabolism of LSD to nor-LSD and 2-oxo-3-hydroxy-LSD: Implications for clinical LSD use. | Luethi, D., et al. 2019. Biochem Pharmacol. 164: 129-138. PMID: 30981875
- A biosensor for measuring NAD+ levels at the point of care. | Yu, Q., et al. 2019. Nat Metab. 1: 1219-1225. PMID: 32694678
- Similar 5F-APINACA Metabolism between CD-1 Mouse and Human Liver Microsomes Involves Different P450 Cytochromes. | Crosby, SV., et al. 2022. Metabolites. 12: PMID: 36005645
- Uninterrupted prolonged ethanol oxidation as a main pathogenetic factor of alcoholic liver damage: evidence from a new liquid diet animal model. | Lindros, KO., et al. 1983. Liver. 3: 79-91. PMID: 6877053
Inhibitor of:
ADH.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
4-Methylpyrazole hydrochloride, 100 mg | sc-214254 | 100 mg | $144.00 | |||
4-Methylpyrazole hydrochloride, 500 mg | sc-214254A | 500 mg | $464.00 |