4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone CAS: 64091-91-4
MF: C10H13N3O2
MW: 207.23
A nitrosamine present in smokeless tobacco that produces cancer in rats and hamsters.

4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone (CAS 64091-91-4)

4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone | CAS 64091-91-4 is rated 4.5 out of 5 by 2.
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Alternate Names: NNK
Application: 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone is a nitrosamine present in smokeless tobacco that produces cancer in rats and hamsters
CAS Number: 64091-91-4
Molecular Weight: 207.23
Molecular Formula: C10H13N3O2
Supplemental Information: This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).

Present in the highest concentrations in smokeless tobacco out of the nitrosamines identified. Readily produces cancer in rats and hamsters.


References

Koenigs, L., et al.: Drug Metab. Dispos., 25, 1407 (1997), Gu, J., et al.: Toxicol. Appl. Pharmacol., 165, 158 (2000), Jalas, J., et al.: Chem. Res. Toxicol., 18, 95(2005), Zhu, L., et al.: Drug Metab. Dispos., 34, 1672(2006),

Physical State :
Solid
Storage :
Store at -20° C
Melting Point :
65-67° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
47289
MDL Number :
MFCD00274580
SMILES :
CN(CCCC(=O)C1=CN=CC=C1)N=O

Download SDS (MSDS)

Certificate of Analysis

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4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone (CAS 64091-91-4)  Product Citations

See how others have used 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone (CAS 64091-91-4). Click on the entry to view the PubMed entry .

Citations 1 to 2 of 2 total

PMID: # 31554629  2019. Cancer Prev Res (Phila).

PMID: # 32326378  Cells. 9:

Citations 1 to 2 of 2 total

We want to study the effects of NKK . So we will use NNK for cell and injection in mice. Do you have any reference that have use your in the last 10 years?

Asked by: Jorge2
Thank you for your question. Unfortunately we have no information regarding this use for our NNK biochemical, we do not have any references that discuss this use.
Answered by: Tech Service
Date published: 2019-09-27
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Rated 4 out of 5 by from Purchased material I bouth this material and it work out well for us.
Date published: 2020-03-26
Rated 5 out of 5 by from Various publications cite the ability of 4 Various publications cite the ability of 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone, a compound present in the highest concentrations in smokeless tobacco out of the nitrosamines identified, to readily produces cancer in rats and hamsters. -SCBT Publication Review
Date published: 2015-01-26
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