4-Methyl-3-nitrophenyl isocyanate (CAS 13471-69-7)
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4-Methyl-3-nitrophenyl isocyanate (4-MNP) is an extensively utilized organic compound in the synthesis of diverse compounds and materials. Its applications span various domains of scientific research, encompassing the synthesis of polymers, and development of biocompatible materials. Within the scientific research field, 4-MNP finds use in synthesizing polymers like hydrogels and polyurethanes. Additionally, 4-MNP plays a role in the synthesis of various organometallic compounds such as organolithium and organozinc compounds. The mechanism of action of 4-Methyl-3-nitrophenyl isocyanate stems from its ability to react with nucleophiles such as hydroxyl groups and amines. This reaction follows a nucleophilic substitution pathway, wherein the hydroxyl group of 4-Methyl-3-nitrophenyl isocyanate is replaced by the isocyanate group of HNCO. Consequently, this reaction yields 4-Methyl-3-nitrophenyl isocyanate and typically an alcohol byproduct.
4-Methyl-3-nitrophenyl isocyanate (CAS 13471-69-7) References
- Synthesis of adducts with amino acids as potential dosimeters for the biomonitoring of humans exposed to toluenediisocyanate. | Sabbioni, G., et al. 2001. Chem Res Toxicol. 14: 1573-83. PMID: 11743739
- D-glucose as a multivalent chiral scaffold for combinatorial chemistry. | Opatz, T., et al. 2002. Carbohydr Res. 337: 2089-110. PMID: 12433474
- Determination of isocyanate specific albumin-adducts in workers exposed to toluene diisocyanates. | Sabbioni, G., et al. 2012. Biomarkers. 17: 150-9. PMID: 22229538
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
4-Methyl-3-nitrophenyl isocyanate, 5 g | sc-226739 | 5 g | $43.00 |