Date published: 2026-5-4

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(4-Methoxybenzyl)triphenylphosphonium chloride (CAS 3462-97-3)

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Alternate Names:
(4-methoxyphenyl)methyl-triphenyl-phosphanium Chloride
CAS Number:
3462-97-3
Purity:
≥96%
Molecular Weight:
418.89
Molecular Formula:
C26H24ClOP
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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(4-Methoxybenzyl)triphenylphosphonium chloride is a quaternary phosphonium salt characterized by its unique structural framework, which combines a triphenylphosphonium core with a 4-methoxybenzyl group. This molecular architecture grants it distinctive physicochemical properties, such as enhanced lipophilicity and stability, making it a compound of interest in various research applications, particularly in organic synthesis and materials science. Its mechanism of action revolves around its ability to facilitate the transfer of the phosphonium ion across different phases, which is exploited in Wittig reactions for the synthesis of alkenes, among other applications. Additionally, the presence of the 4-methoxybenzyl group enhances its reactivity and selectivity in these processes. In materials science, its utility extends to the formation of novel polymers and as a phase transfer catalyst, where its ability to mediate between organic and inorganic phases promotes efficiency and specificity in chemical reactions. The compound′s role in research continues to evolve as new methodologies and applications are developed to leverage its unique chemical properties.


(4-Methoxybenzyl)triphenylphosphonium chloride (CAS 3462-97-3) References

  1. A convergent approach to cryptophycin 52 analogues: synthesis and biological evaluation of a novel series of fragment a epoxides and chlorohydrins.  |  Al-Awar, RS., et al. 2003. J Med Chem. 46: 2985-3007. PMID: 12825938
  2. Pyrene-cored blue-light emitting [4]helicenes: synthesis, crystal structures, and photophysical properties.  |  Hu, JY., et al. 2013. Org Biomol Chem. 11: 2186-97. PMID: 23407903
  3. 4-Phenethyl-1-Propargylpiperidine-Derived Dual Inhibitors of Butyrylcholinesterase and Monoamine Oxidase B.  |  Mazej, T., et al. 2021. Molecules. 26: PMID: 34299393

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

(4-Methoxybenzyl)triphenylphosphonium chloride, 10 g

sc-267608
10 g
$122.00