Date published: 2026-2-7

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4-Methoxybenzyl bromide (CAS 2746-25-0)

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Alternate Names:
4-(Bromomethyl)anisole
CAS Number:
2746-25-0
Molecular Weight:
201.06
Molecular Formula:
C8H9BrO
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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4-Methoxybenzyl Bromide serves as a valuable compound in the study of diarylpyrazoles as inhibitors of cyclooxygenase 2. This compound finds extensive utility across diverse scientific research applications. It is employed in the synthesis of organic compounds and serves as a reagent in various organic reactions, including the synthesis of 4-chlorobenzyl bromide and 4-iodobenzyl bromide.


4-Methoxybenzyl bromide (CAS 2746-25-0) References

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  2. Conformational effects on the activity of drugs. 5. Pharmacological properties of 2-(p-nitrophenyl)-4-isopropylmorpholine, a cyclic analog of INPEA.  |  Del Tacca, M., et al. 1975. J Med Chem. 18: 836-8. PMID: 1174140
  3. Antineoplastic agents. 499. Synthesis of hystatin 2 and related 1H-benzo[de][1,6]-naphthyridinium salts from aaptamine.  |  Pettit, GR., et al. 2004. J Med Chem. 47: 1775-82. PMID: 15027869
  4. Electrophilic alkylations in neutral aqueous or alcoholic solutions.  |  Hofmann, M., et al. 2004. Angew Chem Int Ed Engl. 43: 5402-5. PMID: 15468080
  5. Self-supported and clean one-step cathodic coupling of activated olefins with benzyl bromide derivatives in a micro flow reactor.  |  He, P., et al. 2006. Angew Chem Int Ed Engl. 45: 4146-9. PMID: 16718714
  6. Improved chemical syntheses of 5,6-dihydro-5-fluorouracil.  |  LaFrate, AL. and Katzenellenbogen, JA. 2007. J Org Chem. 72: 8573-6. PMID: 17900141
  7. A scalable synthesis of the IP7 isomer, 5-PP-Ins(1,2,3,4,6)P5.  |  Zhang, H., et al. 2009. Org Lett. 11: 1551-4. PMID: 19253999
  8. Carbon-Silicon Bond Formation in the Synthesis of Benzylic Silanes.  |  Visco, MD., et al. 2016. Org Lett. 18: 2883-5. PMID: 27255675
  9. The Stabilized Cation Pool Method: Metal- and Oxidant-Free Benzylic C-H/Aromatic C-H Cross-Coupling.  |  Hayashi, R., et al. 2016. J Am Chem Soc. 138: 8400-3. PMID: 27341676
  10. Preparation and Applications of 4-Methoxybenzyl Esters in Organic Synthesis.  |  Howard, KT. and Chisholm, JD. 2016. Org Prep Proced Int. 48: 1-36. PMID: 27546912
  11. Design, Herbicidal Activity, and QSAR Analysis of Cycloalka[d]quinazoline-2,4-dione-Benzoxazinones as Protoporphyrinogen IX Oxidase Inhibitors.  |  Wang, DW., et al. 2019. J Agric Food Chem. 67: 9254-9264. PMID: 31356740
  12. Homologation of Electron-Rich Benzyl Bromide Derivatives via Diazo C-C Bond Insertion.  |  Modak, A., et al. 2022. J Am Chem Soc. 144: 86-92. PMID: 34898193
  13. Tumor inhibitors. XI. Proof of structure of aristolochic acid-C by total synthesis of its methyl ester methyl ether.  |  Kupchan, SM., et al. 1965. J Org Chem. 30: 3935-7. PMID: 5846162

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

4-Methoxybenzyl bromide, 1 g

sc-475626
1 g
$142.00