Date published: 2025-12-28

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4-Mercaptopyridine (CAS 4556-23-4)

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Alternate Names:
4-Pyridinethiol
Application:
4-Mercaptopyridine is a probe molecule
CAS Number:
4556-23-4
Molecular Weight:
111.16
Molecular Formula:
C5H5NS
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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4-Mercaptopyridine is a compound that functions as a chelating agent in experimental applications. It acts by forming coordination complexes with metal ions, particularly heavy metals such as mercury, cadmium, and lead. 4-Mercaptopyridine′s mechanism of action involves the formation of stable complexes with metal ions, effectively sequestering them and preventing their interaction with other molecules. At the molecular level, 4-Mercaptopyridine interacts with metal ions through its thiol group, forming coordination bonds and stabilizing the metal complex. 4-Mercaptopyridine′s function as a chelating agent may be useful in experimental applications where the presence of metal ions needs to be controlled or studied.


4-Mercaptopyridine (CAS 4556-23-4) References

  1. Deciphering the near-field response with the far-field wavelength-scanned SERS spectra of 4-mercaptopyridine adsorbed on gold nanocolloidal particles entrapped in Langmuir Reverse Schaefer film of 5CB liquid crystal molecules.  |  Das, SK., et al. 2020. Phys Chem Chem Phys. 22: 8719-8729. PMID: 32270808
  2. Surface-Enhanced Raman Scattering-Active Gold-Decorated Silicon Nanowire Substrates for Label-Free Detection of Bilirubin.  |  Kartashova, AD., et al. 2022. ACS Biomater Sci Eng. 8: 4175-4184. PMID: 34775760
  3. Enhanced charge-transfer induced by conduction band electrons in aluminum-doped zinc oxide/molecule/Ag sandwich structures observed by surface-enhanced Raman spectroscopy.  |  Wang, Y., et al. 2022. J Colloid Interface Sci. 610: 164-172. PMID: 34923264
  4. Double-sided plasmonic metasurface for simultaneous biomolecular separation and SERS detection.  |  Lyu, S., et al. 2023. Spectrochim Acta A Mol Biomol Spectrosc. 285: 121801. PMID: 36122462
  5. Water-phase synthesis of Au and Au-Ag nanowires and their SERS activity.  |  Kichijo, R., et al. 2022. RSC Adv. 12: 28937-28943. PMID: 36320732
  6. Multipolar Raman Scattering vs Interfacial Nanochemistry: Case of 4-Mercaptopyridine on Gold.  |  Mantilla, ABC., et al. 2022. J Am Chem Soc. 144: 20561-20565. PMID: 36343210
  7. An Alkyne-Mediated SERS Aptasensor for Anti-Interference Ochratoxin A Detection in Real Samples.  |  Wang, H., et al. 2022. Foods. 11: PMID: 36360020
  8. Fabrication of gold nanoparticles tethered in heat-cooled calf thymus-deoxyribonucleic acid Langmuir-Blodgett film as effective surface-enhanced Raman scattering sensing platform.  |  Sinha, R., et al. 2022. Front Chem. 10: 1034060. PMID: 36458160
  9. SERS Determination of Oxidative Stress Markers in Saliva Using Substrates with Silver Nanoparticle-Decorated Silicon Nanowires.  |  Kanioura, A., et al. 2023. Biosensors (Basel). 13: PMID: 36832039
  10. Au-NP-Decorated Cotton Swabs as a Facile SERS Substrate for Food-Safety-Related Molecule Detection.  |  Rafiq, F., et al. 2023. ACS Omega. 8: 8541-8547. PMID: 36910972
  11. Plasmonic Nanopillars-A Brief Investigation of Fabrication Techniques and Biological Applications.  |  Ahn, H., et al. 2023. Biosensors (Basel). 13: PMID: 37232896
  12. Phytochemical Characterization and Antimicrobial Activity of Several Allium Extracts.  |  Barbu, IA., et al. 2023. Molecules. 28: PMID: 37241721
  13. 4-Mercaptopyridine-Modified Sensor for the Sensitive Electrochemical Detection of Mercury Ions.  |  Han, M., et al. 2023. Micromachines (Basel). 14: PMID: 37420972

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

4-Mercaptopyridine, 1 g

sc-232805
1 g
$26.00