Date published: 2026-4-5

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4-Mercaptobenzoic Acid (CAS 1074-36-8)

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Alternate Names:
4-Carboxythiophenol
CAS Number:
1074-36-8
Molecular Weight:
154.17
Molecular Formula:
C7H6O2S
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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4-Mercaptobenzoic acid (4-MBA) is a versatile organic compound with the chemical formula C7H6O2S. This colorless solid demonstrates excellent solubility in both water and alcohol. It plays a pivotal role in various industrial applications and holds a significant position in the realm of organic synthesis.This compound serves as a building block for the creation of numerous substances, encompassing dyes,and other organic compounds. In scientific research, 4-Mercaptobenzoic acid proves indispensable, serving multiple purposes such as a reactant in organic synthesis and a probe in biochemical investigations.


4-Mercaptobenzoic Acid (CAS 1074-36-8) References

  1. 4-Mercaptophenylboronic acid SAMs on gold: comparison with SAMs derived from thiophenol, 4-mercaptophenol, and 4-mercaptobenzoic acid.  |  Barriet, D., et al. 2007. Langmuir. 23: 8866-75. PMID: 17636994
  2. Colorimetric detection of Mn2+ using silver nanoparticles cofunctionalized with 4-mercaptobenzoic acid and melamine as a probe.  |  Zhou, Y., et al. 2012. Talanta. 97: 331-5. PMID: 22841088
  3. Surface-enhanced raman scattering detection of pH with silica-encapsulated 4-mercaptobenzoic acid-functionalized silver nanoparticles.  |  Wang, F., et al. 2012. Anal Chem. 84: 8013-9. PMID: 22881392
  4. Vibrational spectroscopy and density functional theory study of 4-mercaptobenzoic acid.  |  Li, R., et al. 2015. Spectrochim Acta A Mol Biomol Spectrosc. 148: 369-74. PMID: 25913136
  5. 4-Mercaptobenzoic acid capped terbium(III)-doped CaF2 nanocrystals: a fluorescent probe for nitroaromatic pollutants.  |  Adusumalli, VNKB., et al. 2019. Mikrochim Acta. 186: 389. PMID: 31152239
  6. Comparison of 4-Mercaptobenzoic Acid Surface-Enhanced Raman Spectroscopy-Based Methods for pH Determination in Cells.  |  Scarpitti, BT., et al. 2020. Appl Spectrosc. 74: 1423-1432. PMID: 32731744
  7. Magnetic polyamidoamine dendrimer grafted with 4-mercaptobenzoic acid as an adsorbent for preconcentration and sensitive determination of polycyclic aromatic hydrocarbons from environmental water samples.  |  Tong, Y., et al. 2021. Talanta. 224: 121884. PMID: 33379093
  8. 4-Mercaptobenzoic acid as a MALDI matrix for highly sensitive analysis of metals.  |  Sun, Q., et al. 2021. Analyst. 146: 1543-1547. PMID: 33565552
  9. 4-Mercaptobenzoic acid-assisted laser desorption/ionization mass spectrometry for sensitive quantification of cesium and strontium in drinking water.  |  Shao, W., et al. 2022. Rapid Commun Mass Spectrom. 36: e9342. PMID: 35729806
  10. Modification of carbon foam with 4-mercaptobenzoic acid functionalised gold nanoparticles for an application in a yeast-based microbial fuel cell.  |  Aliyah, ., et al. 2022. RSC Adv. 12: 28647-28657. PMID: 36320496
  11. Surface-enhanced Raman spectroscopy of one and a few molecules of acid 4-mercaptobenzoic in AgNP enabled by hot spots generated by hydrogen bonding.  |  Marques, FC., et al. 2022. Phys Chem Chem Phys. 24: 27449-27458. PMID: 36341946
  12. Raman spectroscopy study of CdS nanorods and strain induced by the adsorption of 4-mercaptobenzoic acid.  |  Prakash, O. and Umapathy, S. 2023. J Chem Phys. 158: 134719. PMID: 37031145

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

4-Mercaptobenzoic Acid, 1 g

sc-206900
1 g
$95.00