Date published: 2026-5-31

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4-Iodo-1H-pyridin-2-one (CAS 858839-90-4)

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Application:
4-Iodo-1H-pyridin-2-one is a useful chemical for biological applications
CAS Number:
858839-90-4
Purity:
≥97%
Molecular Weight:
221
Molecular Formula:
C5H4INO
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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4-Iodo-1H-pyridin-2-one is a halogenated pyridin-2-one compound. The pyridin-2-one structure bears analogy to pyrimidine heterocycles and the pyridin-2-one moiety forms the core of a series of pharmacolocially relevant inhibitors of HIV-1 reverse transcriptase. The functionalizable iodide substitution of 4-Iodo-1H-pyridin-2-one makes it potentially relevant to the design and study of nucleoside mimics and unnatural base pairs.


4-Iodo-1H-pyridin-2-one (CAS 858839-90-4) References

  1. Synthesis of 6-(2-thienyl)purine nucleoside derivatives that form unnatural base pairs with pyridin-2-one nucleosides.  |  Fujiwara, T., et al. 2001. Bioorg Med Chem Lett. 11: 2221-3. PMID: 11514175
  2. Synthesis and biological evaluation of C-5 methyl substituted 4-arylthio and 4-aryloxy-3-Iodopyridin-2(1H)-one type anti-HIV agents.  |  Guillemont, J., et al. 2009. J Med Chem. 52: 7473-87. PMID: 19645483

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

4-Iodo-1H-pyridin-2-one, 250 mg

sc-262016
250 mg
$294.00

4-Iodo-1H-pyridin-2-one, 1 g

sc-262016A
1 g
$550.00