Molecular structure of 4-Hydroxy Xylazine, CAS Number: 145356-32-7
4-Hydroxy Xylazine (CAS 145356-32-7)
Alternate Names:
4-[(5,6-Dihydro-4H-1,3-thiazin-2-yl)amino]-3,5-dimethylphenol; p-Hydroxyxylazine
Application:
4-Hydroxy Xylazine is a major metabolite of Xylazine
CAS Number:
145356-32-7
Purity:
≥97%
Molecular Weight:
236.33
Molecular Formula:
C12H16N2OS
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
4-Hydroxy Xylazine is a major metabolite of the a2-adrenergic receptor agonist Xylazine, an aniline derivative used as a zoological sedative. 4-Hydroxy Xylazine is particularly important as a marker for identifying the initial presence of Xylazine in the systems of horses in doping control experiments.
4-Hydroxy Xylazine (CAS 145356-32-7) References
- Characterization of metabolites of xylazine produced in vivo and in vitro by LC/MS/MS and by GC/MS. | Mutlib, AE., et al. 1992. Drug Metab Dispos. 20: 840-8. PMID: 1362936
- Determination of xylazine and its metabolites by GC-MS in equine urine for doping analysis. | Spyridaki, MH., et al. 2004. J Pharm Biomed Anal. 35: 107-16. PMID: 15030885
- Re-evaluation of the pharmacokinetics of xylazine administered to Thoroughbred horses. | Habershon-Butcher, J., et al. 2020. J Vet Pharmacol Ther. 43: 6-12. PMID: 31652007
- Doping detection in animals: A review of analytical methodologies published from 1990 to 2019. | Moreira, F., et al. 2021. Drug Test Anal. 13: 474-504. PMID: 33440053
- An ultrasensitive monoclonal antibody-based lateral flow immunoassay for the rapid detection of xylazine in milk. | Chen, L., et al. 2022. Food Chem. 383: 132293. PMID: 35158128
- Serum Metabolomic Alteration in Rats with Osteoarthritis Treated with Palm Tocotrienol-Rich Fraction Alone or in Combination with Glucosamine Sulphate. | Ekeuku, SO., et al. 2023. Life (Basel). 13: PMID: 38137944
- Rapid differentiation of xylazine metabolites using SLIM IM-MS. | Aderorho, R., et al. 2024. Anal Methods.. PMID: 38869241
- Pharmacokinetic study of xylazine in a zebrafish water tank, a human-like surrogate, by liquid chromatography Q-Orbitrap mass spectrometry | Matos R R, Martucci M E P, de Anselmo C S, et al. 2020. Forensic Toxicology. 38: 108-121.
- Untargeted metabolomic profiling on the effect of ginger on rat hepatic changes during ageing | Ekeuku S O, Shahzalli A B A, Tan J K, et al. 2024. Journal of Functional Foods. 113: 106054.
- Xylazine is an agonist at kappa opioid receptors and exhibits sex-specific responses to opioid antagonism | Bedard M L, Huang X P, Murray J G, et al. 2024. Addiction Neuroscience. 11: 100155.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
4-Hydroxy Xylazine, 1 mg | sc-210065 | 1 mg | $360.00 |