Molecular structure of 4-Hydroxy Propofol 4-O-β-D-Glucuronide, CAS Number: 115005-78-2
4-Hydroxy Propofol 4-O-β-D-Glucuronide (CAS 115005-78-2)
Alternate Names:
4-Hydroxy-3,5-bis(1-methylethyl)phenyl β-D-Glucopyranosiduronic Acid
Application:
4-Hydroxy Propofol 4-O-β-D-Glucuronide is A Propofol metabolite
CAS Number:
115005-78-2
Molecular Weight:
370.39
Molecular Formula:
C18H26O8
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
4-Hydroxy Propofol 1-O-β-D-Glucuronide is a metabolite of Propofol (sc-202774) modified at position 4 with an O-linked β-glycosidic bond. Propofol is a phenol derivative that is suggested to modulate the sensitivity of capsaicin (sc-3577) to the transient receptor potential vanilloid subtype-1 (TRPV1) receptor. TRPV1 is a Capsaicin receptor that behaves as a non-selective cation channel that is mainly found in the sensory neurons, and specifically detects painful stimuli, low pH and heat.
4-Hydroxy Propofol 4-O-β-D-Glucuronide (CAS 115005-78-2) References
- Propofol metabolites in man following propofol induction and maintenance. | Favetta, P., et al. 2002. Br J Anaesth. 88: 653-8. PMID: 12067002
- Biosynthesis of drug glucuronides for use as authentic standards. | Soars, MG., et al. 2002. J Pharmacol Toxicol Methods. 47: 161-8. PMID: 12628307
- Effects of coexpression of UGT1A9 on enzymatic activities of human UGT1A isoforms. | Fujiwara, R., et al. 2007. Drug Metab Dispos. 35: 747-57. PMID: 17293379
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
4-Hydroxy Propofol 4-O-β-D-Glucuronide, 1 mg | sc-210059 | 1 mg | $560.00 |