4-Hydroxy Propofol 4-O-beta-D-Glucuronide CAS: 115005-78-2
MF: C18H26O8
MW: 370.39
A Propofol metabolite.

4-Hydroxy Propofol 4-O-β-D-Glucuronide (CAS 115005-78-2)

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Alternate Names: 4-Hydroxy-3,5-bis(1-methylethyl)phenyl β-D-Glucopyranosiduronic Acid
Application: 4-Hydroxy Propofol 4-O-β-D-Glucuronide is A Propofol metabolite
CAS Number: 115005-78-2
Molecular Weight: 370.39
Molecular Formula: C18H26O8
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).

4-Hydroxy Propofol 1-O-β-D-Glucuronide is a metabolite of Propofol (sc-202774) modified at position 4 with an O-linked β-glycosidic bond. Propofol is a phenol derivative that is suggested to modulate the sensitivity of capsaicin (sc-3577) to the transient receptor potential vanilloid subtype-1 (TRPV1) receptor. TRPV1 is a Capsaicin receptor that behaves as a non-selective cation channel that is mainly found in the sensory neurons, and specifically detects painful stimuli, low pH and heat.


References

1. Favetta, P., et al. 2002. Br J Anaesth. 88: 653-658. PMID: 12067002
2. Soars, M.G., et al. 2002. J Pharmacol Toxicol Methods. 47: 161-168. PMID: 12628307
3. Fujiwara, R., et al. 2007. Drug Metab. Dispos. 35: 747-757. PMID: 17293379

Physical State :
Solid
Solubility :
Soluble in Methanol
Storage :
Store at -20° C
Melting Point :
116-118° C
Density :
1.4 g/cm3 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
10384525
SMILES :
CC(C)C1=CC(O[[email protected]]2OC([[email protected]](O)[[email protected]@H](O)[[email protected]]2O)C(O)=O)=CC(C(C)C)=C1O

Download SDS (MSDS)

Certificate of Analysis

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What is the appearance of the compound?

Asked by: two2igm05
Thank you for your question. 4-Hydroxy Propofol 4-O-β-D-Glucuronide, sc-210059, is a white to off-white solid.
Answered by: Chemical Support 4
Date published: 2017-03-24
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