Date published: 2025-11-1

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4-Hydroxy-L-phenylglycine (CAS 32462-30-9)

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Application:
4-Hydroxy-L-phenylglycine is a carnitine palmitoyltransferase-1 inhibitor
CAS Number:
32462-30-9
Purity:
≥99%
Molecular Weight:
167.16
Molecular Formula:
C8H9NO3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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4-Hydroxy-L-phenylglycine is a non-proteinogenic amino acid. It is involved in the synthesis of various important compounds, including antibiotics and other bioactive molecules. This amino acid plays a role in the formation of peptide bonds and is an building block for the production of complex organic molecules. 4-Hydroxy-L-phenylglycine is a key intermediate in the synthesis of many biologically active compounds, making it an important molecule in the field of biochemistry. 4-Hydroxy-L-phenylglycine is an important molecule in biochemistry due to its role in the synthesis of biologically active compounds.


4-Hydroxy-L-phenylglycine (CAS 32462-30-9) References

  1. Redox reaction between amino-(3,4-dihydroxyphenyl)methyl phosphonic acid and dopaquinone is responsible for the apparent inhibitory effect on tyrosinase.  |  Gasowska, B., et al. 2002. Eur J Biochem. 269: 4098-104. PMID: 12180986
  2. In silico analysis of the adenylation domains of the freestanding enzymes belonging to the eucaryotic nonribosomal peptide synthetase-like family.  |  Di Vincenzo, L., et al. 2005. FEBS J. 272: 929-41. PMID: 15691327
  3. Phenylglycine as a novel P2 scaffold in hepatitis C virus NS3 protease inhibitors.  |  Ortqvist, P., et al. 2007. Bioorg Med Chem. 15: 1448-74. PMID: 17113777
  4. Improved P2 phenylglycine-based hepatitis C virus NS3 protease inhibitors with alkenylic prime-side substituents.  |  Lampa, A., et al. 2010. Bioorg Med Chem. 18: 5413-24. PMID: 20541424
  5. Aromatic C-methyltransferases with antipodal stereoselectivity for structurally diverse phenolic amino acids catalyze the methylation step in the biosynthesis of the actinomycin chromophore.  |  Crnovcić, I., et al. 2010. Biochemistry. 49: 9698-705. PMID: 20945860
  6. Protective action of L-carnitine on cardiac mitochondrial function and structure against fatty acid stress.  |  Oyanagi, E., et al. 2011. Biochem Biophys Res Commun. 412: 61-7. PMID: 21791201
  7. A simple, selective, and sensitive gas chromatography-mass spectrometry method for the analysis of five process-related impurities in atenolol bulk drug and capsule formulations.  |  Reddy, AVB., et al. 2017. J Sep Sci. 40: 3086-3093. PMID: 28581679
  8. Comparative Physiological and Metabolic Analysis Reveals a Complex Mechanism Involved in Drought Tolerance in Chickpea (Cicer arietinum L.) Induced by PGPR and PGRs.  |  Khan, N., et al. 2019. Sci Rep. 9: 2097. PMID: 30765803
  9. Macrophages rely on extracellular serine to suppress aberrant cytokine production.  |  Kurita, K., et al. 2021. Sci Rep. 11: 11137. PMID: 34045514
  10. Cellular Metabolomics Profiles Associated With Drug Chemosensitivity in AML.  |  Stockard, B., et al. 2021. Front Oncol. 11: 678008. PMID: 34178663
  11. Improved l-phenylglycine synthesis by introducing an engineered cofactor self-sufficient system.  |  Wang, P., et al. 2022. Synth Syst Biotechnol. 7: 513-521. PMID: 35024478
  12. N-acetyloxfenicine strongly induces mitohormesis in mice as well as in insects.  |  Matsumura, T., et al. 2023. FEBS Lett. 597: 288-297. PMID: 36527170
  13. Azobenzene-Based Amino Acids for the Photocontrol of Coiled-Coil Peptides.  |  Crone, NSA., et al. 2023. Bioconjug Chem. 34: 345-357. PMID: 36705971

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

4-Hydroxy-L-phenylglycine, 5 g

sc-254680A
5 g
$82.00

4-Hydroxy-L-phenylglycine, 10 g

sc-254680
10 g
$109.00