4-Hydroxy Duloxetine-d3 (CAS 1329809-27-9)

4-Hydroxy Duloxetine-d3 is an isotopically labeled analog of 4-Hydroxy Duloxetine, where three hydrogen atoms are replaced with deuterium (D), a heavier isotope of hydrogen. This modification significantly enhances the molecule′s stability, making it an invaluable tool in the field of analytical chemistry, particularly in mass spectrometry-based metabolite profiling and pharmacokinetic studies. The presence of deuterium atoms reduces the rate of in vivo deuterium-hydrogen exchange, thereby providing a more accurate quantification and identification of metabolites. In research, 4-Hydroxy Duloxetine-d3 serves as an internal standard to calibrate and improve the precision of analytical methods when studying the metabolism and disposition of Duloxetine in complex biological matrices. Its role is pivotal in elucidating the metabolic pathways and understanding the biotransformation processes of Duloxetine, contributing to the broader field of drug development and environmental toxicology.