Date published: 2025-11-30

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4-Hydroxy Atorvastatin-d5 Disodium Salt

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Application:
4-Hydroxy Atorvastatin-d5 Disodium Salt is a deuterated metabolite of Atorvastatin
Molecular Weight:
623.63
Molecular Formula:
C33H28D5FN2Na2O6
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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4-Hydroxy Atorvastatin-d5 Disodium Salt is utilized in the field of analytical chemistry as a stable isotope-labeled internal standard for the quantification of 4-hydroxy atorvastatin, a metabolite of atorvastatin, through techniques such as liquid chromatography-tandem mass spectrometry (LC-MS/MS). The deuterium labeling of this compound provides a means to distinguish it from its unlabeled analogs in complex biological matrices, enhancing the precision and accuracy of analytical assays. In biochemical research, 4-Hydroxy Atorvastatin-d5 Disodium Salt is used to study the enzyme kinetics of atorvastatin metabolism and to understand the kinetic properties of statins. It plays a role in research focused on the metabolism of lipids and in the examination of the mechanisms by which the parent compound is processed within the body. Additionally, this compound is critical in the development of robust analytical methods to monitor the presence and concentration of atorvastatin metabolites in biological systems.


4-Hydroxy Atorvastatin-d5 Disodium Salt References

  1. Microdosing Cocktail Assay Development for Drug-Drug Interaction Studies.  |  Chavez-Eng, CM., et al. 2018. J Pharm Sci. 107: 1973-1986. PMID: 29548977

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

4-Hydroxy Atorvastatin-d5 Disodium Salt, 1 mg

sc-216856
1 mg
$600.00

4-Hydroxy Atorvastatin-d5 Disodium Salt, 1 mg

sc-216856-CW
1 mg
$750.00