Date published: 2025-11-21

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4-Fluorophenyl isothiocyanate (CAS 1544-68-9)

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Alternate Names:
p-fluorophenyl isothiocyanate
CAS Number:
1544-68-9
Molecular Weight:
153.18
Molecular Formula:
C7H4FNS
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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4-Fluorophenyl isothiocyanate is an isothiocyanate reagent utilized in organic synthesis, specifically in the production of fluorinated organic compounds. This compound is a handy tool for the precise modification of proteins and various biomolecules. Additionally, it plays a role in creating fluorescent probes and dyes. Beyond its synthetic uses, 4-Fluorophenyl isothiocyanate serves as a valuable resource in the research of cell signaling, apoptosis, and other biological processes. It has demonstrated inhibitory effects against anilines and can curtail the growth of cells in vitro without causing immediate toxicities. Furthermore, it suppresses the formation of RNA and DNA.


4-Fluorophenyl isothiocyanate (CAS 1544-68-9) References

  1. Synthesis of eperezolid-like molecules and evaluation of their antimicrobial activities.  |  Yolal, M., et al. 2012. Bioorg Khim. 38: 610-20. PMID: 23342495
  2. Synthesis and pharmacology of the putative novel muscarinic agonist (S)-4-F-MePyMcN [(S)-4-(pyrrolidino)-1-methyl-2-butynyl-N-(4-fluorophenyl) carbamate oxalate]  |  Saleh Athmani a, Karen N. Bradley b, Alan L. Harvey a b, Edgar Kornisiuk c, Diana Jerusalinsky b. 1998. European Journal of Medicinal Chemistry. 33: 935-941.
  3. Synthesis and Properties of N-(R-Adamantan-1-ylalkyl)-N′-[3(4)-fluorophenyl]thioureas-Target-Oriented Human Soluble Epoxide Hydrolase (hsEH) Inhibitors  |  D. A. Pitushkin, V. V. Burmistrov & G. M. Butov. 2018. Russian Journal of Organic Chemistry. 54: 1469–1474.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

4-Fluorophenyl isothiocyanate, 5 g

sc-232730
5 g
$46.00