Date published: 2026-2-9

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4-Fluoro-N,N-dimethylaniline (CAS 403-46-3)

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CAS Number:
403-46-3
Molecular Weight:
139.17
Molecular Formula:
C8H10FN
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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4-Fluoro-N,N-dimethylaniline is a chemical compound that functions as an intermediate in the synthesis of various organic compounds. It acts as a building block in the production of dyes, pharmaceuticals, and agrochemicals. 4-Fluoro-N,N-Dimethylaniline undergoes chemical reactions to form new carbon-carbon or carbon-heteroatom bonds, allowing for the creation of more complex molecular structures. Its mechanism of action involves participating in substitution reactions, where the fluorine atom and the dimethylamine group can be replaced by other functional groups to introduce specific chemical properties into the resulting molecules. 4-Fluoro-N,N-Dimethylaniline′s role in the synthesis of diverse organic compounds may be a versatile tool for creating new chemical entities with tailored properties for various applications in research and development.


4-Fluoro-N,N-dimethylaniline (CAS 403-46-3) References

  1. Benzyl (phenyl) gamma- and delta-lactones via photoinduced tandem Ar-C, C-O bond formation.  |  Protti, S., et al. 2006. J Am Chem Soc. 128: 10670-1. PMID: 16910648
  2. Simple and sustainable iron-catalyzed aerobic C-H functionalization of N,N-dialkylanilines.  |  Ratnikov, MO., et al. 2013. J Am Chem Soc. 135: 9475-9. PMID: 23734676
  3. Synthesis of Halogenated Anilines by Treatment of N, N-Dialkylaniline N-Oxides with Thionyl Halides.  |  Reed, H., et al. 2018. J Org Chem. 83: 11359-11368. PMID: 30048135
  4. Comment on 'Theoretical Insights into the Excited State Decays of a Donor-Acceptor Dyad: Is the Twisted and Rehybridized Intramolecular Charge-Transfer State Involved?'.  |  Dereka, B., et al. 2020. J Phys Chem B. 124: 10578-10581. PMID: 33169608
  5. Photochemical synthesis of an epigenetic focused tetrahydroquinoline library.  |  Green, AI. and Burslem, GM. 2021. RSC Med Chem. 12: 1780-1786. PMID: 34778779

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

4-Fluoro-N,N-dimethylaniline, 1 g

sc-284232
1 g
$101.00