Molecular structure of 4-Fluoro-α-(2-methyl-1-oxopropyl)-γ-oxo-N,β-diphenyl-benzenebutanamide, CAS Number: 125971-96-2
4-Fluoro-alpha-(2-methyl-1-oxopropyl)-γ-oxo-N,β-diphenyl-benzenebutanamide (CAS 125971-96-2)
Application:
4-Fluoro-α-(2-methyl-1-oxopropyl)-γ-oxo-N,β-diphenyl-benzenebutanamide is an atorvastatin intermediate
CAS Number:
125971-96-2
Molecular Weight:
417.47
Molecular Formula:
C26H24FNO3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
An Atorvastatin intermediate, where atorvastatin is a selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia.
4-Fluoro-alpha-(2-methyl-1-oxopropyl)-γ-oxo-N,β-diphenyl-benzenebutanamide (CAS 125971-96-2) References
- Substituted 2-aminopyridines as inhibitors of nitric oxide synthases. | Hagmann, WK., et al. 2000. Bioorg Med Chem Lett. 10: 1975-8. PMID: 10987430
- Structural mechanism for statin inhibition of HMG-CoA reductase. | Istvan, ES. and Deisenhofer, J. 2001. Science. 292: 1160-4. PMID: 11349148
- Nonpeptide angiotensin II receptor antagonists. 1. Synthesis and in vitro structure-activity relationships of 4-[[[(1H-pyrrol-1-ylacetyl)amino]phenyl]methyl]imidazole derivatives as angiotensin II receptor antagonists. | Sircar, I., et al. 1993. J Med Chem. 36: 1735-45. PMID: 8510101
Inhibitor of:
HMGCR.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
4-Fluoro-α-(2-methyl-1-oxopropyl)-γ-oxo-N,β-diphenyl-benzenebutanamide, 1 g | sc-206880 | 1 g | $200.00 |