Date published: 2025-10-17

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4-Ethyl-2,3-dioxo-1-piperazinecarbonyl Chloride (CAS 59703-00-3)

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CAS Number:
59703-00-3
Molecular Weight:
204.61
Molecular Formula:
C7H9ClN2O3
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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The compound known as 4-Ethyl-2,3-dioxo-1-piperazinecarbonyl Chloride finds widespread usage in scientific research for numerous applications. Primarily, it serves as a coupling reagent during organic synthesis, particularly in the creation of peptides and proteins. This versatile compound acts as a coupling reagent across various chemical reactions, displaying its efficacy as a potent base that readily interacts with acidic groups like carboxylic acids and phosphoric acids. Through this interaction, a covalent bond is formed by the reaction between an electrophile and a nucleophile.


4-Ethyl-2,3-dioxo-1-piperazinecarbonyl Chloride (CAS 59703-00-3) References

  1. Anti-tumor activity of new orally bioavailable 2-amino-5-(thiophen-2-yl)benzamide-series histone deacetylase inhibitors, possessing an aqueous soluble functional group as a surface recognition domain.  |  Hirata, Y., et al. 2012. Bioorg Med Chem Lett. 22: 1926-30. PMID: 22321215
  2. New 5-Aryl-Substituted 2-Aminobenzamide-Type HDAC Inhibitors with a Diketopiperazine Group and Their Ameliorating Effects on Ischemia-Induced Neuronal Cell Death.  |  Hirata, Y., et al. 2018. Sci Rep. 8: 1400. PMID: 29362442
  3. Kinetics model of piperacillin synthesis in a microreactor  |  Yu Xie, Mingjian Feng, Min Zhang, Weiguo Hu, Juan Huang, Yujun Wang, Guangsheng Luo. 2022. Chemical Engineering Science. Volume 259: 117821.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

4-Ethyl-2,3-dioxo-1-piperazinecarbonyl Chloride, 25 g

sc-484965
25 g
$396.00