Date published: 2025-9-29

1-800-457-3801

SCBT Portrait Logo
Seach Input

4-Dimethylamino-1-naphthaldehyde (CAS 1971-81-9)

0.0(0)
Write a reviewAsk a question

Application:
4-Dimethylamino-1-naphthaldehyde is a napthalene compound
CAS Number:
1971-81-9
Purity:
≥95%
Molecular Weight:
199.25
Molecular Formula:
C13H13NO
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

QUICK LINKS

4-Dimethylamino-1-naphthaldehyde, often abbreviated as DMAN, serves a pivotal role in chemical research, particularly in the realm of organic synthesis and fluorescent probe development. Its unique structural features enable it to participate in a variety of chemical reactions, making it an invaluable tool for constructing complex organic molecules. One of the key mechanisms by which 4-Dimethylamino-1-naphthaldehyde operates is through its ability to act as an electrophile, readily undergoing nucleophilic addition reactions. This reactivity is harnessed in the synthesis of heterocyclic compounds and in Schiff base formation, where it reacts with primary amines to form imine linkages, a fundamental step in the synthesis of many organic compounds. Additionally, its fluorescence properties are exploited in the design of molecular probes, where it serves as a fluorescent moiety in the detection and quantification of biomolecules. Through these diverse applications, 4-Dimethylamino-1-naphthaldehyde significantly contributes to advancements in chemical research, offering a versatile tool for exploring molecular interactions and facilitating the development of novel compounds with potential applications in various fields of scientific inquiry.


4-Dimethylamino-1-naphthaldehyde (CAS 1971-81-9) References

  1. Salivary aldehyde dehydrogenase: activity towards aromatic aldehydes and comparison with recombinant ALDH3A1.  |  Giebułtowicz, J., et al. 2009. Molecules. 14: 2363-72. PMID: 19633610
  2. Synthesis of fluorescent enone derived alpha-amino acids.  |  Fowler, LS., et al. 2009. Org Biomol Chem. 7: 4309-16. PMID: 19795073
  3. Antitumor agents. 284. New desmosdumotin B analogues with bicyclic B-ring as cytotoxic and antitubulin agents.  |  Nakagawa-Goto, K., et al. 2011. J Med Chem. 54: 1244-55. PMID: 21284385
  4. Recent advances in the synthesis and application of fluorescent α-amino acids.  |  Harkiss, AH. and Sutherland, A. 2016. Org Biomol Chem. 14: 8911-8921. PMID: 27714204
  5. Synthesis and Topoisomerase I inhibitory properties of klavuzon derivatives.  |  Akçok, İ., et al. 2017. Bioorg Chem. 71: 275-284. PMID: 28242062
  6. Mosquito odorant receptor sensitive to natural spatial repellents and inhibitory compounds.  |  Xu, P., et al. 2022. Insect Biochem Mol Biol. 144: 103763. PMID: 35364281
  7. A Multiplex Assay to Assess the Transaminase Activity toward Chemically Diverse Amine Donors.  |  Czarnievicz, N., et al. 2023. Chembiochem. 24: e202200614. PMID: 36385460

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

4-Dimethylamino-1-naphthaldehyde, 1 g

sc-226617
1 g
$153.00