Molecular structure of 4-Deoxy-D-glucose, CAS Number: 7286-46-6
4-Deoxy-D-glucose (CAS 28434-38-0)
CAS Number:
28434-38-0
Molecular Weight:
164.16
Molecular Formula:
C6H12O5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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4-Deoxy-D-glucose is a potential inhibitor for beta-1,4-Gal-T1 (lactose synthase). 4-Deoxy-D-glucose, a modified glucose analogue with an additional hydroxyl group at the fourth carbon, possesses a unique characteristic that renders it resistant to glucokinase metabolism. This feature enables 4-Deoxy-D-glucose to selectively target specific metabolic pathways.
4-Deoxy-D-glucose (CAS 28434-38-0) References
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- Creation of the first anomeric D/L-sugar kinase by means of directed evolution. | Hoffmeister, D., et al. 2003. Proc Natl Acad Sci U S A. 100: 13184-9. PMID: 14612558
- Biological evaluation of a series of 2-acetamido-2-deoxy-D-glucose analogs towards cellular glycosaminoglycan and protein synthesis in vitro. | Berkin, A., et al. 2005. Glycoconj J. 22: 443-51. PMID: 16311889
- Imino sugars are potent agonists of the human glucose sensor SGLT3. | Voss, AA., et al. 2007. Mol Pharmacol. 71: 628-34. PMID: 17110502
- Transglycosylic reactions of nucleotides of deoxy-sugars. 3-Deoxy-D-glucose, 4-deoxy-D-glucose and 6-deoxy-D-glucose incorporation into glycogen. | Zemek, J., et al. 1973. Eur J Biochem. 40: 195-9. PMID: 4589548
- Immunochemical studies on dextrans. IV. Further characterization of the determinant groups on various dextrans involved in their reactions with the homologous human antidextrans. | Torii, M., et al. 1966. J Immunol. 96: 797-805. PMID: 5913753
- Active renal hexose transport. Structural requirements. | Kleinzeller, A., et al. 1980. Biochim Biophys Acta. 600: 513-29. PMID: 7407126
- Stimulation of the gerbil's gustatory receptors by monosaccharides. | Jakinovich, W. and Goldstein, IJ. 1976. Brain Res. 110: 491-504. PMID: 947469
Inhibitor of:
β-1,4-Gal-T1.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
4-Deoxy-D-glucose, 25 mg | sc-220937 | 25 mg | $323.00 |