4-Cyanobenzohydrazide (CAS 43038-36-4)
CAS Number:
43038-36-4
Molecular Weight:
161.16
Molecular Formula:
C8H7N3O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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4-Cyanobenzohydrazide (4-CBA) is an important reagent in organic synthesis, particularly in the preparation of substituted amines and heterocycles. It acts as a nucleophile, attacking the electrophilic carbon atom of an aryl halide. This reaction results in the formation of an intermediate hydrazone, which then undergoes a cyclization reaction to form the final product. 4-Cyanobenzohydrazide is also used as a fluorescent dye in biochemical and physiological studies, as a photolabile protecting group for peptides and proteins, and as a ligand for metal ions, such as copper and zinc, to form coordination complexes.
4-Cyanobenzohydrazide (CAS 43038-36-4) References
- Structural basis and SAR for G007-LK, a lead stage 1,2,4-triazole based specific tankyrase 1/2 inhibitor. | Voronkov, A., et al. 2013. J Med Chem. 56: 3012-23. PMID: 23473363
- Design, Synthesis, and Preclinical Characterization of the Selective Androgen Receptor Modulator (SARM) RAD140. | Miller, CP., et al. 2011. ACS Med Chem Lett. 2: 124-9. PMID: 24900290
- Synthesis, molecular docking study and in vitro thymidine phosphorylase inhibitory potential of oxadiazole derivatives. | Ullah, H., et al. 2018. Bioorg Chem. 78: 58-67. PMID: 29533215
- Novel Conjugated s-Tetrazine Derivatives Bearing a 4H-1,2,4-Triazole Scaffold: Synthesis and Luminescent Properties. | Maj, A., et al. 2022. Molecules. 27: PMID: 35056774
- Novel Inhibitors of Acetyl- and Butyrylcholinesterase Derived from Benzohydrazides: Synthesis, Evaluation and Docking Study. | Houngbedji, NH., et al. 2023. Pharmaceuticals (Basel). 16: PMID: 37259322
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
4-Cyanobenzohydrazide, 500 mg | sc-316237 | 500 mg | $258.00 |