Date published: 2026-5-12

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4-Chloroaniline (CAS 106-47-8)

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CAS Number:
106-47-8
Molecular Weight:
127.57
Molecular Formula:
C6H6ClN
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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4-Chloroaniline (4-CA) is an aromatic amine compound. The extensive research conducted in recent years has explored the potential applications of 4-Chloroaniline across diverse fields. 4-Chloroaniline finds utility in numerous scientific research applications. It acts as a chemical reagent in the synthesis of heterocyclic compounds such as pyridines and quinolines. Moreover, 4-Chloroaniline plays a significant role in the production of biocides, essential for managing microbial growth in industrial and agricultural settings.


4-Chloroaniline (CAS 106-47-8) References

  1. Toxicity of 4-chloroaniline in early life stages of zebrafish (Danio rerio): II. Cytopathology and regeneration of liver and gills after prolonged exposure to waterborne 4-chloroaniline.  |  Burkhardt-Holm, P., et al. 1999. Arch Environ Contam Toxicol. 37: 85-102. PMID: 10341046
  2. Biodegradation of 4-chloroaniline by bacteria enriched from soil.  |  Vangnai, AS. and Petchkroh, W. 2007. FEMS Microbiol Lett. 268: 209-16. PMID: 17328747
  3. Hepatic microsomal N-hydroxylation of aniline and 4-chloroaniline by rainbow trout (Onchorhyncus mykiss).  |  Dady, JM., et al. 1991. Xenobiotica. 21: 1605-20. PMID: 1785206
  4. Oxidation of 4-chloroaniline studied by on-line electrochemistry electrospray ionization mass spectrometry.  |  Zettersten, C., et al. 2009. Anal Chem. 81: 5180-7. PMID: 19563209
  5. Oligomerization of 4-chloroaniline by oxidoreductases.  |  Simmons, KE., et al. 1987. Environ Sci Technol. 21: 999-1003. PMID: 19994999
  6. Determination of 4-chloroaniline and its derivatives formed in the interaction of sodium hypochlorite and chlorhexidine by using gas chromatography.  |  Basrani, BR., et al. 2010. J Endod. 36: 312-4. PMID: 20113798
  7. Biodegradation of 2-chloroaniline, 3-chloroaniline, and 4-chloroaniline by a novel strain Delftia tsuruhatensis H1.  |  Zhang, LL., et al. 2010. J Hazard Mater. 179: 875-82. PMID: 20417029
  8. Stimulation of Bacillus sp. by lipopeptide biosurfactant for the degradation of aromatic amine 4-Chloroaniline.  |  Femina Carolin, C., et al. 2021. J Hazard Mater. 415: 125716. PMID: 34088195
  9. Host-guest modes and supramolecular frameworks of complexes of tetramethyl cucurbit[6]uril with 4-chloroaniline and 4,4'-diaminostilbene.  |  Meng, Y., et al. 2021. RSC Adv. 11: 3470-3475. PMID: 35424315
  10. Electrochemical study of 4-chloroaniline in a water/acetonitrile mixture. A new method for the synthesis of 4-chloro-2-(phenylsulfonyl)aniline and N-(4-chlorophenyl)benzenesulfonamide.  |  Mohamadighader, N., et al. 2020. RSC Adv. 10: 31563-31569. PMID: 35520680
  11. Chloroperoxidase-catalysed oxidation of 4-chloroaniline to 4-chloronitrosobenze.  |  Corbett, MD., et al. 1978. Biochem J. 175: 353-60. PMID: 743200
  12. Oligomers of 4-chloroaniline are intermediates formed during its biodegradation by Phanerochaete chrysosporium.  |  Chang, CW. and Bumpus, JA. 1993. FEMS Microbiol Lett. 107: 337-42. PMID: 8472915
  13. Tissue distribution, subcellular localization and covalent binding of 2-chloroaniline and 4-chloroaniline in Fischer 344 rats.  |  Dial, LD., et al. 1998. Toxicology. 131: 109-19. PMID: 9928626

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

4-Chloroaniline, 250 g

sc-356883
250 g
$36.00

4-Chloroaniline, 1 kg

sc-356883A
1 kg
$122.00