Date published: 2026-2-13

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4-Chloro-8-quinolinol (CAS 57334-36-8)

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CAS Number:
57334-36-8
Molecular Weight:
179.60
Molecular Formula:
C9H6ClNO
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Has an antifungal activity against Aspergillus niger, A. oryzae, Myrothecium verrucaria, Trichophyton mentagrophytes and Trichoderma viride. 4-Chloro-8-quinolinol, or 4-CQO, is a white crystalline solid from the quinolin-8-ol compound family. It dissolves readily in water and other organic solvents. Extensive research has explored the diverse applications of 4-Chloro-8-quinolinol in the realms of chemistry, biology, and medicine. In the field of chemistry, it serves as a valuable starting material for synthesizing compounds like 4-chloroquinoline-8-sulfonate and 4-chloroquinoline-8-carboxylic acid. In biology, it has garnered attention for its potential as an inhibitor of enzymes involved in drug and xenobiotic metabolism.


4-Chloro-8-quinolinol (CAS 57334-36-8) References

  1. A new type of 8-quinolinol amebacidal agent  |  Burckhalter, J. H., & Edgerton, W. H. 1951. Journal of the American Chemical Society. 73(10): 4837-4839.
  2. Comparison of reliability of log P values calculated from a group contribution approach and from the autocorrelation method  |  Devillers, J., & Domine, D. 1997. SAR and QSAR in Environmental Research. 7(1-4): 195-232.
  3. Preparation and fungitoxicity of some trichloro-, tribromo-, tetrachloro-, and tetrabromo-8-quinolinols  |  Gershon, H., Clarke, D. D., & Gershon, M. 2001. Monatshefte für Chemie/Chemical Monthly. 132: 1075-1080.
  4. Effect of Dimethyl Sulfoxide and Dimethylformamide on the Stability of 4-Halo-8-quinolinols.  |  Gershon, H., Clarke, D. D., & McMahon, J. J. 2003. Monatshefte für Chemie/Chemical Monthly. 134: 1099-1104.
  5. 5-Alkyl-8-hydroxyquinolines: synthesis and application in dye-sensitized solar cells  |  Manthou, V. S., Perganti, D., Rotas, G., Falaras, P., & Vougioukalakis, G. C. 2017. Synlett. 28(08): 929-933.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

4-Chloro-8-quinolinol, 25 mg

sc-210010
25 mg
$326.00