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4-Chloro-6-methoxy Indole (CAS 93490-31-4)

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Alternate Names:
4-Chloro-6-Methoxy-1H-indole
Application:
4-Chloro-6-methoxy Indole is is a promutagen from fava beans
CAS Number:
93490-31-4
Molecular Weight:
181.62
Molecular Formula:
C9H8ClNO
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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4-Chloro-6-methoxy Indole is actively studied for its role as an intermediate in the synthesis of a variety of complex organic molecules. It is a key reagent in the field of organic synthesis, where researchers explore its reactivity in various chemical transformations. The compound′s utility in catalytic reactions is of particular interest, as it is often involved in the formation of new bonds through cross-coupling reactions. In materials science, 4-Chloro-6-methoxy Indole is investigated for its potential incorporation into organic electronic materials due to its indolic structure, which can contribute to desirable electronic properties. Additionally, it is employed in the discovery of new ligands for transition metal catalysts, aiding in the development of more efficient and selective synthetic routes. The compound′s role in the synthesis of natural products and analogs thereof is another significant area of application, supporting the advancement of organic chemistry and related disciplines.


4-Chloro-6-methoxy Indole (CAS 93490-31-4) References

  1. Mutagenic activities of tryptophan metabolites before and after nitrite treatment.  |  Hashizume, T., et al. 1991. Food Chem Toxicol. 29: 839-44. PMID: 1765329
  2. In-vitro testing and the carcinogenic potential of several nitrosated indole compounds.  |  Tiedink, HG., et al. 1991. Cell Biol Toxicol. 7: 371-86. PMID: 1794111
  3. The stability of the nitrosated products of indole, indole-3-acetonitrile, indole-3-carbinol and 4-chloroindole.  |  Tiedink, HG., et al. 1989. Food Chem Toxicol. 27: 723-30. PMID: 2693284
  4. 32P-postlabeling analysis of DNA adducts in rat stomach with 1-nitrosoindole-3-acetonitrile, a direct-acting mutagenic indole compound formed by nitrosation.  |  Yamashita, K., et al. 1988. Carcinogenesis. 9: 1905-7. PMID: 3168167
  5. Alkylating activity in food products--especially sauerkraut and sour fermented dairy products--after incubation with nitrite under quasi-gastric conditions.  |  Groenen, PJ. and Busink, E. 1988. Food Chem Toxicol. 26: 215-25. PMID: 3366423
  6. Induction of oral cavity cancer by 3-diazotyramine, a nitrosated product of tyramine present in foods.  |  Fujita, Y., et al. 1987. Carcinogenesis. 8: 527-9. PMID: 3829319
  7. 4-Chloro-6-methoxyindole is the precursor of a potent mutagen (4-chloro-6-methoxy-2-hydroxy-1-nitroso-indolin-3-one oxime) that forms during nitrosation of the fava bean (Vicia faba).  |  Yang, D., et al. 1984. Carcinogenesis. 5: 1219-24. PMID: 6548421

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

4-Chloro-6-methoxy Indole, 10 mg

sc-210003
10 mg
$380.00