Date published: 2026-2-4

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4-Chloro-3-nitrobenzoyl chloride (CAS 38818-50-7)

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CAS Number:
38818-50-7
Molecular Weight:
220.01
Molecular Formula:
C7H3Cl2NO3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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4-Chloro-3-nitrobenzoyl chloride functions as a chemical intermediate. It acts as an acylating agent, reacting with various nucleophiles to form amides, esters, and other derivatives. The mechanism of action involves the substitution of the chlorine atom with a nucleophile, leading to the formation of a new chemical compound. This process occurs through nucleophilic acyl substitution, where the nucleophile attacks the carbonyl carbon of the acyl chloride, resulting in the displacement of the chloride ion. 4-Chloro-3-Nitrobenzoyl Chloride may play a role in the synthesis of agrochemicals, and other organic compounds, contributing to the development of new materials and compounds for experimental purposes.


4-Chloro-3-nitrobenzoyl chloride (CAS 38818-50-7) References

  1. Synthesis and biological evaluation of novel sulfonanilide compounds as antiproliferative agents for breast cancer.  |  Su, B., et al. 2008. J Comb Chem. 10: 475-83. PMID: 18380483
  2. Discovery of AMG 853, a CRTH2 and DP Dual Antagonist.  |  Liu, J., et al. 2011. ACS Med Chem Lett. 2: 326-30. PMID: 24900313
  3. Discovery of N-(2-aminoethyl)-N-benzyloxyphenyl benzamides: New potent Trypanosoma brucei inhibitors.  |  Buchynskyy, A., et al. 2017. Bioorg Med Chem. 25: 1571-1584. PMID: 28187957
  4. A Multipronged Approach Establishes Covalent Modification of β-Tubulin as the Mode of Action of Benzamide Anti-cancer Toxins.  |  Povedano, JM., et al. 2020. J Med Chem. 63: 14054-14066. PMID: 33180487

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

4-Chloro-3-nitrobenzoyl chloride, 25 g

sc-232569
25 g
$36.00