Date published: 2025-12-19

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4-Chloro-3-nitro-5-sulfamoylbenzoic Acid (CAS 22892-96-2)

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CAS Number:
22892-96-2
Molecular Weight:
280.64
Molecular Formula:
C7H5ClN2O6S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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4-Chloro-3-nitro-5-sulphamoylbenzoic acid (CNSA) participates in the generation of a nitrobenzoic acid radical intermediate, which subsequently undergoes nucleophilic attack to form an amide or ester functional group. 4-Chloro-3-nitro-5-sulphamoylbenzoic acid serves as an intermediate in the production of Bumetanide. Additionally, 4-Chloro-3-nitro-5-sulphamoylbenzoic acid may impact the activity of specific receptors, including G-protein coupled receptors.


4-Chloro-3-nitro-5-sulfamoylbenzoic Acid (CAS 22892-96-2) References

  1. Discovery and optimization of antibacterial AccC inhibitors.  |  Cheng, CC., et al. 2009. Bioorg Med Chem Lett. 19: 6507-14. PMID: 19875284
  2. Ultrasound mediated catalyst free synthesis of 6H-1-benzopyrano[4,3-b]quinolin-6-ones leading to novel quinoline derivatives: their evaluation as potential anti-cancer agents.  |  Mulakayala, N., et al. 2012. Bioorg Med Chem. 20: 759-68. PMID: 22202437
  3. When inhibitors do not inhibit: critical evaluation of rational drug design targeting chorismate mutase from Mycobacterium tuberculosis.  |  Munack, S., et al. 2012. Chem Biodivers. 9: 2507-27. PMID: 23161632

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

4-Chloro-3-nitro-5-sulfamoylbenzoic Acid, 100 mg

sc-209995
100 mg
$320.00