Molecular structure of 4-Bromosalicylic acid, CAS Number: 1666-28-0
4-Bromosalicylic acid (CAS 1666-28-0)
Alternate Names:
4-Bromo-2-hydroxybenzoic acid
CAS Number:
1666-28-0
Purity:
≥98%
Molecular Weight:
217.02
Molecular Formula:
C7H5BrO3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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4-Bromosalicylic acid is a phenolic compound classified as a brominated hydroxybenzoic acid. It appears as a white crystalline solid that exhibits limited solubility in water but readily dissolves in organic solvents. 4-Bromosalicylic acid holds great significance as an intermediate in the synthesis of diverse organic compounds. Its reactivity and high solubility in organic solvents make it a valuable reagent in laboratory experiments. It has found application in studies related to polymer synthesis, and enzyme inhibition. The precise mechanism of action underlying 4-Bromosalicylic acid′s effects remains incompletely understood. However, it is believed to function as an antioxidant by scavenging free radicals and impeding oxidative damage.
4-Bromosalicylic acid (CAS 1666-28-0) References
- 5'-O-[(N-acyl)sulfamoyl]adenosines as antitubercular agents that inhibit MbtA: an adenylation enzyme required for siderophore biosynthesis of the mycobactins. | Qiao, C., et al. 2007. J Med Chem. 50: 6080-94. PMID: 17967002
- Novel salicylanilides from 4,5-dihalogenated salicylic acids: Synthesis, antimicrobial activity and cytotoxicity. | Paraskevopoulos, G., et al. 2017. Bioorg Med Chem. 25: 1524-1532. PMID: 28126437
- Varying degrees of homostructurality in a series of cocrystals of antimalarial drug 11-azaartemisinin with salicylic acids. | Roy, M., et al. 2021. Acta Crystallogr C Struct Chem. 77: 262-270. PMID: 34089249
- Cd-Doped Polyoxotitanium Nanoclusters with a Modifiable Organic Shell for Photoelectrochemical Water Splitting. | Wu, YX., et al. 2021. Inorg Chem. 60: 19263-19269. PMID: 34817992
- Synthesis and biological evaluation of orally active prodrugs and analogs of para-aminosalicylic acid (PAS). | Hegde, PV., et al. 2022. Eur J Med Chem. 232: 114201. PMID: 35219151
- Effect of modulator ligands on the growth of Co2(dobdc) nanorods. | Pappas, NS. and Mason, JA. 2023. Chem Sci. 14: 4647-4652. PMID: 37152265
- Synthesis and immunosuppressive activity of amino alcohol containing coumarin and benzothiophene | , et al. (2016). Chemical Research in Chinese Universities. volume 32,: pages 357–365.
- Synthesis and characterization of copolymers from 4-halo(chloro, bromo) salicylic acid | , et al. (1982). Proceedings of the Indian Academy of Sciences - Chemical Sciences. volume 91,: pages 173–183.
- Preparation and Chelating Properties of 4-Bromosalicylic Acid-Formaldehyde Polymers. Part II | H. S. Patel and & S. R. Patel. 1982 -. Journal of Macromolecular Science: Part A - Chemistry. Volume 17, Issue 9: Pages 1383-1398.
- Structure-toxicity assessment of metabolites of the aerobic bacterial transformation of substituted naphthalenes | and Jeffrey D. LeBlond, B ruce M. Applegate, Fu-Minn Menn, T. Wayne Schultz, Gary S. Sayler. May 2000. Environmental Toxicology and Chemistry. Volume19, Issue5: Pages 1235-1246.
- Control of 11-Aza:4-X-SalA Cocrystal Polymorphs Using Heteroseeds That Switch On/Off Halogen Bonding | by Keyao Li, et al. 2022. Crystals., 12(10),: 1368.
- Artemisinin–acetylenedicarboxylic acid cocrystal: screening, structure determination, and physicochemical property characterisation† | Jay Makadia,a Shadrack J. Madu,a Randolph Arroo, ORCID logo a Colin C. Seaton ORCID logo b and Mingzhong Li ORCID logo *a. 2022,. CrystEngComm,. 24,: 1056-1067.
- Role of halogen bonding in clathrate formation of tetra- and hexasalicylides derived from halogenated salicylic acids | . 21 January 2013,. Tetrahedron. Volume 69, Issue 3,: Pages 1120-1127.
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| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
4-Bromosalicylic acid, 5 g | sc-256730 | 5 g | $59.00 |