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4-(Bromomethyl)-6,7-dimethoxycoumarin (CAS 88404-25-5)

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Application:
4-(Bromomethyl)-6,7-dimethoxycoumarin is an HPLC fluorescent labeling reagent
CAS Number:
88404-25-5
Molecular Weight:
299.12
Molecular Formula:
C12H11BrO4
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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4-(Bromomethyl)-6,7-dimethoxycoumarin is a reagent for the covalent fluorescent labeling of compounds. 4-(Bromomethyl)-6,7-dimethoxycoumarin is described to react with nucleophilic amino acid residues to introduce the fluorescent tag to protein samples and to react with carboxylic acids for derivatization and determination by HPLC.


4-(Bromomethyl)-6,7-dimethoxycoumarin (CAS 88404-25-5) References

  1. Coumarin substrates for cytochrome P450 2D6 fluorescence assays.  |  Nakamura, K., et al. 2001. Anal Biochem. 292: 280-6. PMID: 11355862
  2. Deactivation behavior and excited-state properties of (coumarin-4-yl)methyl derivatives. 2. Photocleavage of selected (coumarin-4-yl)methyl-caged adenosine cyclic 3',5'-monophosphates with fluorescence enhancement.  |  Eckardt, T., et al. 2002. J Org Chem. 67: 703-10. PMID: 11856009
  3. Labeling the (Ca(2+)-Mg2+)-ATPase of sarcoplasmic reticulum with 4-(bromomethyl)-6,7-dimethoxycoumarin: detection of conformational changes.  |  Stefanova, HI., et al. 1992. Biochemistry. 31: 6023-31. PMID: 1385723
  4. 2-propyl-1-aminopentane, its deamination by monoamine oxidase and semicarbazide-sensitive amine oxidase, conversion to valproic acid and behavioral effects.  |  Yu, PH. and Davis, BA. 1991. Neuropharmacology. 30: 507-15. PMID: 1865997
  5. 4-Hydroxy-7-methyl-3-phenylcoumarin Suppresses Aflatoxin Biosynthesis via Downregulation of aflK Expressing Versicolorin B Synthase in Aspergillus flavus.  |  Moon, YS., et al. 2017. Molecules. 22: PMID: 28468270
  6. Investigation of derivatization reagents for the analysis of diarrhetic shellfish poisoning toxins by liquid chromatography with fluorescence detection.  |  Marr, JC., et al. 1994. Nat Toxins. 2: 302-11. PMID: 7866666
  7. Simultaneous radiometric and fluorimetric detection of lauric acid metabolites using high-performance liquid chromatography following esterification with 4-bromomethyl-6,7-dimethoxycoumarin in human and rat liver microsomes.  |  Amet, Y., et al. 1996. J Chromatogr B Biomed Appl. 681: 233-9. PMID: 8811432
  8. 4-Bromomethyl-6,7-dimethoxycoumarin as a fluorescent label for carboxylic acids in chromatographic detection  |  Farinotti, R., Siard, P., Bourson, J., Kirkiacharian, S., Valeur, B., & Mahuzier, G. 1983. Journal of Chromatography A. 269: 81-90.
  9. BrMOZPhC, a novel coumarin type reagent for the fluorescent derivatisation of carboxylic acids  |  Gikas, E., Parissi-Poulou, M., Kazanis, M., & Vavagianis, A. 2003. Analytica chimica acta. 489(2): 153-163.
  10. Properties of a new fluorescent coumarin derivatization reagent employing molecular modelling techniques  |  Gikas, E., Parissi-Poulou, M., Kazanis, M., & Vavagiannis, A. 2005. Journal of Molecular Structure: THEOCHEM. 724(1-3): 135-142.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

4-(Bromomethyl)-6,7-dimethoxycoumarin, 1 g

sc-206768
1 g
$214.00