4-Bromocrotonic Acid (CAS 13991-36-1)
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CAS Number:
13991-36-1
Molecular Weight:
164.99
Molecular Formula:
C4H5BrO2
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
4-Bromocrotonic acid is a simple unsaturated carboxylic acid. The presence of both the carboxylic acid group and the bromine atom allows 4-bromocrotonic acid to participate in a variety of chemical reactions. This acid finds utility in synthesizing a diverse array of compounds and materials. It has been used in synthesizing manufacturing polymers. Furthermore, it has served as a catalyst for organic reactions. It demonstrates reactivity with a wide range of compounds, including alcohols, amines, and other organic substances. Moreover, it can undergo self-reaction to form esters and amides, and it readily forms salts when reacting with other acids.
4-Bromocrotonic Acid (CAS 13991-36-1) References
- Mechanism of inhibition of insulin-stimulated glucose transport by 4-bromocrotonic acid in 3T3-L1 adipocytes. | Chai, SP. and Fong, JC. 2003. Cell Signal. 15: 269-77. PMID: 12531425
- NMR studies of beta-oxidation and short-chain fatty acid metabolism during recovery of reperfused hearts. | Lewandowski, ED., et al. 1991. Am J Physiol. 261: H354-63. PMID: 1877663
- Effect of Toxicants on Fatty Acid Metabolism in HepG2 Cells. | Grünig, D., et al. 2018. Front Pharmacol. 9: 257. PMID: 29740314
- Effects of the fatty acid blocking agents, oxfenicine and 4-bromocrotonic acid, on performance in aerobic and ischemic myocardium. | Molaparast-Saless, F., et al. 1987. J Mol Cell Cardiol. 19: 509-20. PMID: 3625784
- Fatty acid oxidation in rat brain is limited by the low activity of 3-ketoacyl-coenzyme A thiolase. | Yang, SY., et al. 1987. J Biol Chem. 262: 13027-32. PMID: 3654601
- Evaluation of inhibitors of fatty acid oxidation in rat myocytes. | el-Aleem, SA. and Schulz, H. 1987. Biochem Pharmacol. 36: 4307-12. PMID: 3689454
- Effect of fatty acid oxidation on efficiency of energy production in rat heart. | Hütter, JF., et al. 1985. Am J Physiol. 249: H723-8. PMID: 4051011
- Inhibition of fatty acid oxidation and decrease of oxygen consumption of working rat heart by 4-bromocrotonic acid. | Hütter, JF., et al. 1984. J Mol Cell Cardiol. 16: 105-8. PMID: 6699916
- 4-Bromocrotonic acid, an effective inhibitor of fatty acid oxidation and ketone body degradation in rat heart mitochondria. On the rate-determining step of beta-oxidation and ketone body degradation in heart. | Olowe, Y. and Schulz, H. 1982. J Biol Chem. 257: 5408-13. PMID: 7068598
- The relationship between mitochondrial activation and toxicity of some substituted carboxylic acids. | Yao, KW., et al. 1994. Chem Biol Interact. 90: 225-34. PMID: 8168171
- Stimulation of myocyte insulin-responsive glucose transporters by the inhibition of fatty acid oxidation. | Abdel-aleem, S., et al. 1993. Diabetes Res. 22: 11-9. PMID: 8200180
- Regulation of glucose utilization during the inhibition of fatty acid oxidation in rat myocytes. | Abdel-aleem, S., et al. 1994. Horm Metab Res. 26: 88-91. PMID: 8200620
- Differential inhibition of lipolysis by 2-bromopalmitic acid and 4-bromocrotonic acid in 3T3-L1 adipocytes. | Fong, JC., et al. 1997. Biochim Biophys Acta. 1344: 65-73. PMID: 9022756
- 4-Bromocrotonic acid enhances basal but inhibits insulin-stimulated glucose transport in 3T3-L1 adipocytes. | Leu, SJ., et al. 1998. Biochem Biophys Res Commun. 244: 11-4. PMID: 9514876
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
4-Bromocrotonic Acid, 1 g | sc-486695 | 1 g | $351.00 |