Date published: 2026-5-18

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4-Bromo-N-methylbenzylamine (CAS 699-03-6)

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Alternate Names:
(4-Bromobenzyl)methylamine
CAS Number:
699-03-6
Molecular Weight:
200.08
Molecular Formula:
C8H10BrN
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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4-Bromo-N-methylbenzylamine is a chemical compound that is frequently utilized in the field of organic chemistry for various research applications. It is of particular interest in transition metal-catalyzed cross-coupling reactions where the bromine atom serves as a leaving group, enabling the formation of carbon-nitrogen bonds. This compound is also an important intermediate in the synthesis of more complex organic molecules, including pharmaceuticals and agrochemicals. In studies of amine reactivity, 4-Bromo-N-methylbenzylamine provides insights into the steric and electronic effects of substituents on aromatic rings. Moreover, it is used in the development of novel organocatalysts and in the functionalization of surfaces and polymers, where the pendant amine group can be employed for further derivatization.


4-Bromo-N-methylbenzylamine (CAS 699-03-6) References

  1. Novel cyclopentane dicarboxamide sodium channel blockers as a potential treatment for chronic pain.  |  Shao, PP., et al. 2005. Bioorg Med Chem Lett. 15: 1901-7. PMID: 15780630
  2. Discovery of vaniprevir (MK-7009), a macrocyclic hepatitis C virus NS3/4a protease inhibitor.  |  McCauley, JA., et al. 2010. J Med Chem. 53: 2443-63. PMID: 20163176
  3. Arylpiperidines as a new class of oxidosqualene cyclase inhibitors.  |  Keller, M., et al. 2016. Eur J Med Chem. 109: 13-22. PMID: 26745812
  4. A New Derivatization Reagent for HPLC-MS Analysis of Biological Organic Acids.  |  Marquis, BJ., et al. 2017. Chromatographia. 80: 1723-1732. PMID: 29213145
  5. High Coverage Profiling of Carboxylated Metabolites in HepG2 Cells Using Secondary Amine-Assisted Ultrahigh-Performance Liquid Chromatography Coupled to High-Resolution Mass Spectrometry.  |  Zheng, J., et al. 2021. Anal Chem. 93: 1604-1611. PMID: 33356171
  6. Sensitive quantification of short-chain fatty acids combined with global metabolomics in microbiome cultures.  |  Lin, W., et al. 2023. Chem Commun (Camb). 59: 5843-5846. PMID: 37098752

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

4-Bromo-N-methylbenzylamine, 1 g

sc-232493
1 g
$40.00

4-Bromo-N-methylbenzylamine, 5 g

sc-232493A
5 g
$84.00

4-Bromo-N-methylbenzylamine, 10 g

sc-232493B
10 g
$133.00

4-Bromo-N-methylbenzylamine, 25 g

sc-232493C
25 g
$270.00

4-Bromo-N-methylbenzylamine, 100 g

sc-232493D
100 g
$791.00