Date published: 2026-5-27

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4-Bromo-3-chlorobenzaldehyde (CAS 120077-69-2)

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CAS Number:
120077-69-2
Molecular Weight:
219.46
Molecular Formula:
C7H4BrClO
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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4-Bromo-3-chlorobenzaldehyde (4-BCBA) is a versatile aromatic aldehyde widely employed in both scientific and industrial domains. As a halogenated aldehyde, it has found extensive use in various organic syntheses, particularly those involving the production of heterocyclic compounds. The utilization of 4-Bromo-3-chlorobenzaldehyde spans a broad spectrum of scientific research applications. It has served as a key component in the synthesis of heterocyclic compounds such as pyridines, quinolines, and indoles. Although the precise mechanism of action for 4-Bromo-3-chlorobenzaldehyde remains incompletely understood, it is believed to function as a pro-electrophile in organic synthesis reactions, exhibiting remarkable versatility through diverse transformations. Specifically, 4-Bromo-3-chlorobenzaldehyde can undergo nucleophilic addition, substitution, and elimination reactions. Additionally, it can be employed as both a catalyst and a reagent in an array of organic syntheses.


4-Bromo-3-chlorobenzaldehyde (CAS 120077-69-2) References

  1. Discovery and Optimization of a 4-Aminopiperidine Scaffold for Inhibition of Hepatitis C Virus Assembly.  |  Rolt, A., et al. 2021. J Med Chem. 64: 9431-9443. PMID: 34184537
  2. Discovery of benzo[d]isothiazole derivatives as novel scaffold inhibitors targeting the programmed cell death-1/programmed cell death-ligand 1 (PD-1/PD-L1) interaction through 'ring fusion' strategy.  |  Gao, Y., et al. 2022. Bioorg Chem. 123: 105769. PMID: 35405572
  3. Identification and Strategies to Mitigate High Total Clearance of Benzylamine-Substituted Biphenyl Ring Systems.  |  Williamson, B., et al. 2022. Mol Pharm. 19: 2115-2132. PMID: 35533086

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

4-Bromo-3-chlorobenzaldehyde, 1 g

sc-483596
1 g
$23.00