Date published: 2026-4-5

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4-Benzoylpiperidine Hydrochloride (CAS 25519-80-6)

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CAS Number:
25519-80-6
Molecular Weight:
225.71
Molecular Formula:
C12H16ClNO
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Synthetic intermediate in the preparation of CNS depressants.


4-Benzoylpiperidine Hydrochloride (CAS 25519-80-6) References

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  2. New diarylmethylpiperazines as potent and selective nonpeptidic delta opioid receptor agonists with increased In vitro metabolic stability.  |  Plobeck, N., et al. 2000. J Med Chem. 43: 3878-94. PMID: 11052793
  3. N,N-Diethyl-4-(phenylpiperidin-4-ylidenemethyl)benzamide: a novel, exceptionally selective, potent delta opioid receptor agonist with oral bioavailability and its analogues.  |  Wei, ZY., et al. 2000. J Med Chem. 43: 3895-905. PMID: 11052794
  4. The 'reverse-tethered' ruthenium (II) catalyst for asymmetric transfer hydrogenation: further applications.  |  Morris, DJ., et al. 2006. J Org Chem. 71: 7035-44. PMID: 16930059
  5. Synthesis and in vivo brain distribution of carbon-11-labeled δ-opioid receptor agonists.  |  Pichika, R., et al. 2010. Nucl Med Biol. 37: 989-96. PMID: 21055630
  6. Synthesis and in vitro biological evaluation of carbonyl group-containing analogues for σ1 receptors.  |  Wang, W., et al. 2011. J Med Chem. 54: 5362-72. PMID: 21732626
  7. Synthesis and anticancer evaluation of 6-azacyclonol-2,4,6-trimethylpyridin-3-ol derivatives: M3 muscarinic acetylcholine receptor-mediated anticancer activity of a cyclohexyl derivative in androgen-refractory prostate cancer.  |  Karmacharya, U., et al. 2021. Bioorg Chem. 110: 104805. PMID: 33725508
  8. Aroylpiperidines and pyrrolidines. A new class of potent central nervous system depressants.  |  Duncan, RL., et al. 1970. J Med Chem. 13: 1-6. PMID: 5460893
  9. Benzenesulfenamides as antihypertensive agents. Substituted piperidine and 1-arylpiperazine derivatives.  |  Klioze, SS., et al. 1980. J Med Chem. 23: 677-9. PMID: 7392034

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

4-Benzoylpiperidine Hydrochloride, 100 mg

sc-216783
100 mg
$360.00