Molecular structure of 4-Azido-L-phenylalanine, CAS Number: 33173-53-4
4-Azido-L-phenylalanine (CAS 33173-53-4)
See product citations (3)
Alternate Names:
4-Azido-L-phenylalanine is also known as (S)-2-Amino-3-p-azidophenylpropionic acid.
Application:
4-Azido-L-phenylalanine is an unnatural derivative of L-phenylalanine and an effective vibrational reporter of local protein environments.
CAS Number:
33173-53-4
Purity:
≥98%
Molecular Weight:
206.10
Molecular Formula:
C9H10N4O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
4-Azido-L-phenylalanine is also known as H-4-Azido-Phe-OH, L-Phe(4-azido)-OH, π-Azido-L-phenylalanine, p-Azido-Phenylalanine, 4-azidophenylalanine, and (S)-2-Amino-3-(4-azidophenyl)propanoic acid. 4-Azido-L-phenylalanine is an unnatural derivative of L-phenylalanine, a nonpolar, essential amino acid that naturally occurs in the human body. 4-Azido-L-phenylalanine is used as an effective vibrational reporter of local protein environments and can be incorporated by recombinant methods into proteins allowing site-specific modification. Detection sensitivity with 4-Azido-L-phenylalanine in 1-D gels and Western blots is in the low femtomole range and compatible with downstream LC-MS/MS and MALDI MS analysis.
4-Azido-L-phenylalanine (CAS 33173-53-4) References
- Addition of p-azido-L-phenylalanine to the genetic code of Escherichia coli. | Chin, JW., et al. 2002. J Am Chem Soc. 124: 9026-7. PMID: 12148987
- Sensitive, site-specific, and stable vibrational probe of local protein environments: 4-azidomethyl-L-phenylalanine. | Bazewicz, CG., et al. 2013. J Phys Chem B. 117: 8987-93. PMID: 23865850
- Rapid and simultaneous screening of 47,XXY and AZF microdeletions by quadruplex real-time polymerase chain reaction. | Zhou, Y., et al. 2015. Reprod Biol. 15: 113-21. PMID: 26051460
- Preparation, Characterization, and Oxygenase Activity of a Photocatalytic Artificial Enzyme. | Gu, Y., et al. 2015. Chembiochem. 16: 1880-1883. PMID: 26097041
- Engineering a dirhodium artificial metalloenzyme for selective olefin cyclopropanation. | Srivastava, P., et al. 2015. Nat Commun. 6: 7789. PMID: 26206238
- Synthesis and Protein Incorporation of Azido-Modified Unnatural Amino Acids. | Tookmanian, EM., et al. 2015. RSC Adv. 5: 1274-1281. PMID: 26478813
- Copy Number Variations of the Azoospermia Factor Region and SRY Are Not Associated with the Risk of Hypospadias. | Kon, M., et al. 2016. Sex Dev. 10: 12-5. PMID: 27023068
- Pseudoautosomal abnormalities in terminal AZFb+c deletions are associated with isochromosomes Yp and may lead to abnormal growth and neuropsychiatric function. | Castro, A., et al. 2017. Hum Reprod. 32: 465-475. PMID: 28057878
- Synthesis and Explosion Hazards of 4-Azido-l-phenylalanine. | Richardson, MB., et al. 2018. J Org Chem. 83: 4525-4536. PMID: 29577718
- Identifying and Modulating Accidental Fermi Resonance: 2D IR and DFT Study of 4-Azido-l-phenylalanine. | Zhang, J., et al. 2018. J Phys Chem B. 122: 8122-8133. PMID: 30067030
- Characterization and Scaled-Up Production of Azido-Functionalized Silk Fiber Produced by Transgenic Silkworms with an Expanded Genetic Code. | Teramoto, H., et al. 2019. Int J Mol Sci. 20: PMID: 30708986
- Engineering a methyllysine reader with photoactive amino acid in mammalian cells. | Arora, S., et al. 2020. Chem Commun (Camb). 56: 12210-12213. PMID: 32926023
- Effect of isotope substitution on the Fermi resonance and vibrational lifetime of unnatural amino acids modified with IR probe: A 2D-IR and pump-probe study of 4-azido-L-phenyl alanine. | Park, JY., et al. 2020. J Chem Phys. 153: 164309. PMID: 33138413
- Generation of Fluorescent Versions of Saccharomyces cerevisiae RPA to Study the Conformational Dynamics of Its ssDNA-Binding Domains. | Kuppa, S., et al. 2021. Methods Mol Biol. 2281: 151-168. PMID: 33847957
- Site-specific nanobody-oligonucleotide conjugation for super-resolution imaging. | Teodori, L., et al. 2022. J Biol Methods. 9: e159. PMID: 35510035
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
4-Azido-L-phenylalanine, 100 mg | sc-289923B | 100 mg | $179.00 | |||
4-Azido-L-phenylalanine, 250 mg | sc-289923 | 250 mg | $274.00 | |||
4-Azido-L-phenylalanine, 1 g | sc-289923A | 1 g | $713.00 | |||
4-Azido-L-phenylalanine, 5 g | sc-289923C | 5 g | $1989.00 |