4-Aminopyridin-3-ol hydrochloride (CAS 52334-53-9)
QUICK LINKS
4-Aminopyridin-3-ol hydrochloride, often abbreviated as 4-AP HCl, is a white crystalline solid that has the ability to dissolve in water and other polar solvents. This organic compound is noteworthy for its broad applications in scientific research, particularly within the domains of biochemistry and physiology. It has been recognized for its role as an inhibitor of voltage-gated sodium channels, which play a critical part in the propagation of electrical signals within the nervous system. By binding to these channels, 4-Aminopyridin-3-ol hydrochloride can block the passage of sodium ions through them, thus inhibiting the transmission of electrical signals. Furthermore, it has been employed in the exploration of the impacts of neurotoxins, like botulinum toxin, on neuronal excitability. It has also been utilized to investigate the influence of various substances on the excitation of neurons.
4-Aminopyridin-3-ol hydrochloride (CAS 52334-53-9) References
- Target-Focused Library Design by Pocket-Applied Computer Vision and Fragment Deep Generative Linking. | Eguida, M., et al. 2022. J Med Chem. 65: 13771-13783. PMID: 36256484
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
4-Aminopyridin-3-ol hydrochloride, 1 g | sc-261674 | 1 g | $388.00 | |||
4-Aminopyridin-3-ol hydrochloride, 5 g | sc-261674A | 5 g | $1571.00 |