Date published: 2025-9-30

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4-Aminophenylphosphorylcholine (CAS 102185-28-4)

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Alternate Names:
p-Aminophenylphosphorylcholine; PAPPC
Application:
4-Aminophenylphosphorylcholine is used in the preparation of affinity columns for various protein purifications
CAS Number:
102185-28-4
Molecular Weight:
274.25
Molecular Formula:
C11H19N2O4P
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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4-Aminophenylphosphorylcholine is primarily researched for its role as a substrate in the study of phospholipase D (PLD) activity. PLD is an enzyme that catalyzes the hydrolysis of phosphatidylcholine to produce phosphatidic acid and choline, a reaction that is significant in various cellular processes including membrane trafficking and signal transduction. In research applications, 4-Aminophenylphosphorylcholine is used to better understand these mechanisms. Additionally, it is applied in the investigation of lipid-mediated signaling pathways, as alterations in PLD activity have been associated with a number of cellular functions. The chemical has also been utilized in the synthesis of phosphatidic acid analogs that are used in further biochemical studies to delineate the diverse roles of phospholipids in cells.


4-Aminophenylphosphorylcholine (CAS 102185-28-4) References

  1. National pholcodine consumption and prevalence of IgE-sensitization: a multicentre study.  |  Johansson, SG., et al. 2010. Allergy. 65: 498-502. PMID: 19796197
  2. Strategies To Achieve Control over the Surface Ratio of Two Different Components on Modified Electrodes Using Aryldiazonium Salts.  |  Jiang, C., et al. 2016. Langmuir. 32: 2509-17. PMID: 26901641
  3. Hydrophilic Micro- and Macroelectrodes with Antibiofouling Properties for Biomedical Applications.  |  Ruhunage, CK., et al. 2022. ACS Biomater Sci Eng. 8: 2920-2931. PMID: 35710337
  4. Phosphorylcholine-conjugated gold-molecular clusters improve signal for Lymph Node NIR-II fluorescence imaging in preclinical cancer models.  |  Baghdasaryan, A., et al. 2022. Nat Commun. 13: 5613. PMID: 36153336
  5. A novel phosphorylcholine-binding protein from rat serum and its effect on heparin-lipoprotein complex formation in the presence of calcium.  |  Nagpurkar, A. and Mookerjea, S. 1981. J Biol Chem. 256: 7440-6. PMID: 6788770
  6. Purification of rabbit C-reactive protein by affinity precipitation with thermosensitive polymer.  |  Mori, S., et al. 1994. Protein Expr Purif. 5: 153-6. PMID: 8054848
  7. Effect of environmental pollutants on the C-reactive protein of a freshwater major carp, Catla catla.  |  Paul, I., et al. 1998. Dev Comp Immunol. 22: 519-32. PMID: 9877434

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

4-Aminophenylphosphorylcholine, 25 mg

sc-206826
25 mg
$265.00

4-Aminophenylphosphorylcholine, 100 mg

sc-206826A
100 mg
$842.00

4-Aminophenylphosphorylcholine, 250 mg

sc-206826B
250 mg
$1533.00

4-Aminophenylphosphorylcholine, 1 g

sc-206826C
1 g
$3060.00

4-Aminophenylphosphorylcholine, 10 g

sc-206826D
10 g
$9858.00